, Volume 181, Issue 11–12, pp 915–920 | Cite as

Severe Paracoccidioidomycosis in a 14-Year-Old Boy

  • L. P. Ruas
  • R. M. Pereira
  • F. G. Braga
  • X. T. Lima
  • R. L. Mamoni
  • M. L. Cintra
  • A. Z. Schreiber
  • V. L. G. Calich
  • M. H. S. L. BlottaEmail author


Paracoccidioidomycosis (PCM) is the most important systemic mycoses in Latin America. We describe a severe case of paracoccidioidomycosis in a 14-year-old boy, with a rapid disease progression. The fungal strain was isolated and inoculated into a T and/or B cell immunocompromised mice, which revealed a highly virulent strain. The case report presented herein emphasizes the importance of considering PCM in the differential diagnosis of patients with other infectious diseases in endemic areas and highlights a novel isolate.


Paracoccidioidomycosis Case report Virulent strain Fungal infection 


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • L. P. Ruas
    • 1
  • R. M. Pereira
    • 2
  • F. G. Braga
    • 1
  • X. T. Lima
    • 1
    • 4
  • R. L. Mamoni
    • 1
  • M. L. Cintra
    • 3
  • A. Z. Schreiber
    • 1
  • V. L. G. Calich
    • 5
  • M. H. S. L. Blotta
    • 1
    Email author
  1. 1.Department of Clinical Pathology, School of Medical SciencesState University of Campinas (UNICAMP)CampinasBrazil
  2. 2.Department of Pediatrics, School of Medical SciencesState University of Campinas (UNICAMP)CampinasBrazil
  3. 3.Department of Pathology, School of Medical SciencesState University of Campinas (UNICAMP)CampinasBrazil
  4. 4.School of MedicineUniversity of Fortaleza (UNIFOR)FortalezaBrazil
  5. 5.Department of Immunology, Institute of Biomedical SciencesUniversity of São PauloSão PauloBrazil

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