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Occurrence of Arthroderma benhamiae Genotype in Japan

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Abstract

In this study, we epidemiologically investigated on clinical isolates of Arthroderma benhamiae from humans and animals in Japan by internal transcribed spacer (ITS) region sequence analysis and mating type (MAT)-specific PCR. Seven of 8 A. benhamiae isolates from a human, rabbits and guinea pigs were identified as group I (white phenotype) by morphological characters and ITS region sequence analysis. One strain isolated from a degus (Octodon degus) produced colonies with few irregular folds and yellow velvety mycelium without macro- and microconidia. This strain resembled to group II (yellow phenotype) strain. ITS sequence analysis was also 100 % identical to that of group II. MAT-specific PCR indicated that 6 of these 7 isolates of group I contained an alpha-box gene and that one strain contained high-mobility-group (HMG) gene. One strain of group II was revealed to have an alpha-box gene and no HMG gene. To our knowledge, it is the first A. benhamiae isolate of group II found in Japan. The A. benhamiae may be more widespread in worldwide than our surpassing what is common or usual or expected.

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Acknowledgments

This study was partly funded by Health, Labor and Welfare Sciences Research Grants for Research on Measures for Intractable Diseases (H25 shinko-ippan 006) from the Japanese Government.

Conflict of interest

The authors have no conflict interest.

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Author notes

  1. Rui Kano

    Present address: Department of Pathobiology, Nihon University School of Veterinary Medicine, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan

Authors and Affiliations

  1. Department of Dermatology, Tokyo Medical University, 6-1-1 Nishishinjuku, Shinjukuku, Tokyo, 160-0023, Japan

    Junichiro Hiruma, Kazutoshi Harada & Ryoji Tsuboi

  2. Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

    Michel Monod

  3. Ochanomizu Institute for Medical Mycology and Allergology, Nakamura Bldg. 2F, 2-12-4 Hongo, Bunkyoku, Tokyo, 113-0033, Japan

    Masataro Hiruma

  4. Teikyo University Institute of Medical Mycology, 539 Otsuka, Hachioji, Tokyo, 192-0395, Japan

    Atsuhiko Hasegawa

Authors
  1. Junichiro Hiruma
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  2. Rui Kano
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  3. Kazutoshi Harada
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  4. Michel Monod
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  5. Masataro Hiruma
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  6. Atsuhiko Hasegawa
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  7. Ryoji Tsuboi
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Corresponding author

Correspondence to Rui Kano.

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Hiruma, J., Kano, R., Harada, K. et al. Occurrence of Arthroderma benhamiae Genotype in Japan. Mycopathologia 179, 219–223 (2015). https://doi.org/10.1007/s11046-014-9839-0

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  • DOI: https://doi.org/10.1007/s11046-014-9839-0

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