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Alternaria arborescens Infection in a Healthy Individual and Literature Review of Cutaneous Alternariosis

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Abstract

A 28-year-old man presented at our clinic with 1-month history of an ulcer covered with crust on his left anterior tibia. Based on the morphological features and molecular identification, the patient was diagnosed as cutaneous alternariosis caused by Alternaria arborescens. He was successfully cured by oral itraconazole and topical use of 0.25 % liposomal amphotericin B. A review of published studies revealed 29 cases of cutaneous alternariosis. Most cases (90 %) occurred in immunosuppressed patients; itraconazole (59 %) and voriconazole (24 %) are the most effective treatments of choices.

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Authors and Affiliations

  1. Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China

    Wenying Hu, Yuping Ran, Kaiwen Zhuang & Jebina Lama

  2. State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China

    Chaoliang Zhang

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  1. Wenying Hu
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  2. Yuping Ran
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  3. Kaiwen Zhuang
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  4. Jebina Lama
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  5. Chaoliang Zhang
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Correspondence to Yuping Ran.

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Hu, W., Ran, Y., Zhuang, K. et al. Alternaria arborescens Infection in a Healthy Individual and Literature Review of Cutaneous Alternariosis. Mycopathologia 179, 147–152 (2015). https://doi.org/10.1007/s11046-014-9822-9

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  • DOI: https://doi.org/10.1007/s11046-014-9822-9

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