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Schizophillum commune Causing Sinusitis with Nasal Polyposis in the Sub-Himalayan Region: First Case Report and Review

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Abstract

Schizophillum commune is an environmental fungus rarely causing human infections of diverse nature. Sinusitis occurs in immunocompromised persons and seldom in healthy subjects. Though easily isolated, the lack of awareness of its virulence is a bottleneck in the diagnosis of this infection. We report the first case of S. commune sinusitis with nasal polyps in an immunocompetent male from the sub-Himalayan region. The computerized tomography scan findings established the clinical diagnosis, and causative agent was confirmed as S. commune. A white, woolly mold with septate, hyaline hyphae and characteristic spicules but unclamped connections suggested a monokaryotic isolate. Patient was treated successfully with fiberoptic endoscopic sinus surgery, and no antifungal therapy was instituted. There was no recurrence at review after 1 year.

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References

  1. Sigler L, Estrada S, Montealegre NA. Maxillary sinusitis caused by Schizophillum commune and experience with treatment. J Med Vet Mycol. 1997;35:365–70.

    Article  CAS  PubMed  Google Scholar 

  2. Premamalini T, Ambujavalli BT, Anitha S, Somu L, Kindo AJ. Schizophillum commune a causative agent of fungal sinusitis: A case report. Case Rep Infect Dis. 2011; 2011; doi:10.1155/2011/821259.

  3. Infections due to miscellaneous molds. In: Kwon-Chung KJ, Bennett JE, editors. Medical Mycology. Philadelphia: Lea & Febiger;1992. p. 733–767.

  4. Swain B, Panigrahy R, Panigrahy D. Schizophillum commune sinusitis in an immunocompetent host. Indian J Med Microbiol. 2011;29(4):439–42.

    CAS  PubMed  Google Scholar 

  5. Nazeri M, Ardehali MM, Moazeni M. A case of fungus ball type pansinusitis caused by Schizophillum commune. Med Mycol Cas Rep. 2012;1(1):115–8.

    Article  Google Scholar 

  6. Watling R, Sweeney J. Observations on Schizophillum commune. Sabouraudia. 1974;12:214–26.

    Article  Google Scholar 

  7. Kern ME, Uecker FA. Maxillary sinus infection caused by the homobasidiomycetous fungus Schizophillum commune. J Clin Microbiol. 1986;23(6):1001–5.

    CAS  PubMed Central  PubMed  Google Scholar 

  8. Kligman A. A basidiomycete probably causing onychomycosis. J Invest Dermatol. 1950;14:67–70.

    CAS  PubMed  Google Scholar 

  9. Batista AD, Maia JA, Singer R. Basidioneuromycosis of man. An Soc Biol Pernambuco. 1955;13:52–60.

    Google Scholar 

  10. McGinnis MR. Detection of fungi in cerebrospinal fluid. Am J Med. 1983;75(1B):129–38.

    Article  CAS  PubMed  Google Scholar 

  11. Restrepo A, Greer DL, Robledo M, Osorio O, Mondragon H. Ulceration of the palate caused by a basidiomycete Schizophillum commune. Sabouraudia. 1973;11:201–4.

    Article  CAS  PubMed  Google Scholar 

  12. Chowdhary A, Randhawa HS, Gaur SN. Schizophillum commune as an emerging fungal pathogen: a review and report of two cases. Mycoses. 2013;56(1):1–10.

    Article  CAS  PubMed  Google Scholar 

  13. Greer DL, Bolanos B. Pathogenic potential of Schizophillum commune isolated from a human case. Sabouraudia. 1974;12:233–44.

    Article  Google Scholar 

  14. Sigler L, Bartley JR, Parr DH, Morris AJ. Maxillary sinusitis caused by medusoid form of Schizophillum commune. J Clin Microbiol. 1999;37(10):3395–8.

    CAS  PubMed Central  PubMed  Google Scholar 

  15. Roh ML, Tuazon CU, Mandler R, Kwon-Chung KJ, Geist CE. Sphenocavernous sinus syndrome associated with Schizophillum commune infection of the sphenoid sinus. Ophthal Plast Reconstr Surg. 2005;21:71–4.

    Article  PubMed  Google Scholar 

  16. Adhikary R, Joshi S. Comment on: Schizophillum commune sinusitis in an immunocompetent host. Indian J Med Microbiol. 2012;30(2):249–54.

    Article  CAS  PubMed  Google Scholar 

  17. Castro LA, Alvarez MI, Martinez E. Case report of Schizophillum commune in an immunocompetent patient. Colomb Med. 2010;41(1):71–5.

    Google Scholar 

  18. Raper JR, Krongelb GS. Genetic and environmental aspects of fruiting in Schizophillum commune. Mycologia. 1958;50:707–40.

    Article  Google Scholar 

  19. Toussaint MG, Lachaud L, Pihet M. Chronic sinusitis due to Schizophillum commune. About two new cases. J Med Mycol. 2011;21(4):289–93.

    Article  Google Scholar 

  20. Ahmed MK, Ishino T, Takeno S, Hirakawa K. Bilateral allergic fungal rhinosinusitis caused by Schizophillum commune and Aspergillus niger. A case report. Rhinology. 2009;47:217–21.

    PubMed  Google Scholar 

  21. Kamei K, Unno H, Nagao K, Kuriyama T, Nishimura K, Miyaji M. Allergic bronchopulmonary mycosis caused by the basidiomycetous fungus Schizophillum commune. Clin Infect Dis. 1994;18:305–9.

    Article  CAS  PubMed  Google Scholar 

  22. Rihs JD, Padhye AA, Good CB. Brain abscess caused by Schizophillum commune: an emerging basidiomycete pathogen. J Clin Microbiol. 1996;34(7):1628–32.

    CAS  PubMed Central  PubMed  Google Scholar 

  23. Peric A, Vojvodic D, Zolotarevski L, Peric A. Nasal polyposis and fungal Schizophillum commune infection: a case report. Acta Medica Hradec Kralone. 2011;54(2):83–6.

    Google Scholar 

  24. Clark S, Campbell CK, Sandison A, Choa DI. Schizophillum commune: an unusual isolate from a patient with allergic fungal sinusitis. J Infect. 1996;32(2):147–50.

    Article  CAS  PubMed  Google Scholar 

  25. Rosenthal J, Katz R, Du Bois DB, Morrissey A, Machicao A. Chronic maxillary sinusitis associated with the mushroom Schizophillum commune in a patient with AIDS. Clin Infect Dis. 1992;14(1):46–8.

    Article  CAS  PubMed  Google Scholar 

  26. Buzina W, Braun H, Freudenchuss K, Lacker A, Schimpl K, Stammberger H. The basidiomycete Schizophillum commune in paranasal sinuses. Mycoses. 2003;46(Suppl 1):23–7.

    CAS  PubMed  Google Scholar 

  27. Taguchi K, Oharaseki T, Yokouchi Y. Allergic fungal sinusitis caused by Bipolaris spicifera and Schizophillum commune. Med Mycol. 2007;45(6):559–64.

    Article  PubMed  Google Scholar 

  28. Catalano P, Lawson W, Bottone E, Lebenger J. Basidiomycetous (mushroom) infection of the maxillary sinus. Otolaryngol –Head Neck Surg. 1990; 102(2): 183–185.

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Acknowledgments

The authors gratefully acknowledge the contribution of Prof. Arunaloke Chakrabarti (Head, Dept. of Microbiology and National Centre for Collection of Pathogenic Fungi, PGIMER, Chandigarh) toward identification and confirmation of the isolate as S. commune.

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Correspondence to Poonam Gupta.

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Verma, S., Gupta, P., Singh, D. et al. Schizophillum commune Causing Sinusitis with Nasal Polyposis in the Sub-Himalayan Region: First Case Report and Review. Mycopathologia 177, 103–110 (2014). https://doi.org/10.1007/s11046-013-9717-1

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  • DOI: https://doi.org/10.1007/s11046-013-9717-1

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