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Acremonium strictum: Report of a Rare Emerging Agent of Cutaneous Hyalohyphomycosis with Review of Literatures

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Abstract

We present a case of cutaneous hyalohyphomycosis due to Acremonium strictum in an immunocompetent individual along with an overview of fungal infections caused by A. strictum. The diagnosis was confirmed by the presence of hyphae in microscopic examination of cutaneous biopsy and discharge, positive culture for A. strictum and sequencing of the isolate at reference centre. The infection resolved with itraconazole and terbinafine. Cutaneous or subcutaneous infections of A. strictum have rarely been reported. Fungemia or disseminated infection often with fatal outcome in immunocompromised patients was the most common presentation of A. strictum infection found in the literatures. The studies also reveal worldwide variation in the treatment regime and outcome of the treatment.

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Acknowledgments

We gratefully acknowledge Mrs. Sunita Gupta, National Culture Collection of Pathogenic Fungi (Mycology Division), Centre of Advance Research in Medical Mycology & WHO Collaborating Centre, Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India, for her help in molecular typing of the isolate.

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Authors and Affiliations

  1. Department of Microbiology, Gauhati Medical College, Guwahati, 781032, Assam, India

    Ajanta Sharma & N. K. Hazarika

  2. Department of Microbiology, Jorhat Medical College, Jorhat, 785001, Assam, India

    Purnima Barua

  3. Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

    M R Shivaprakash & Arunaloke Chakrabarti

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  1. Ajanta Sharma
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  2. N. K. Hazarika
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  4. M R Shivaprakash
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  5. Arunaloke Chakrabarti
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Correspondence to Ajanta Sharma.

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Sharma, A., Hazarika, N.K., Barua, P. et al. Acremonium strictum: Report of a Rare Emerging Agent of Cutaneous Hyalohyphomycosis with Review of Literatures. Mycopathologia 176, 435–441 (2013). https://doi.org/10.1007/s11046-013-9709-1

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  • DOI: https://doi.org/10.1007/s11046-013-9709-1

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