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Extensive Deep Dermatophytosis Cause by Trichophyton rubrum in a Patient with Liver Cirrhosis and Chronic Renal Failure

Mycopathologia volume 176, pages 457–462 (2013)Cite this article

Abstract

Dermatophytes are the main pathogen of superficial skin fungal infections. On rare occasions, they can cause deep and extensive infections, especially in immunocompromised hosts. We reported a 48-year-old patient with liver cirrhosis and chronic renal failure who developed an extensive deep dermatophytosis with possible hematogenous dissemination. Skin histopathology showed extensive involvement of hair follicles and dermis by fungal elements. The pathogen was cultured from both skin biopsy specimen and central venous line. It was identified as Trichophyton rubrum by morphology and further conformed by sequencing of internal transcribed spacers of ribosomal DNA. The patient died quickly before the identification was available.

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Authors and Affiliations

  1. Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan

    Lung-Chi Wu & Yun-Ting Chang

  2. Department of Internal Medicine, Taichung Armed Forces General Hospital, Taichung, Taiwan

    Lung-Chi Wu

  3. National Defense Medical Center, Taipei, Taiwan

    Lung-Chi Wu

  4. Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan

    Pei-Lun Sun

  5. Institute of Ecology and Evolutionary Biology, National Taiwan University, Taipei, Taiwan

    Pei-Lun Sun

  6. Department of Dermatology, National Yang-Ming University, No. 201, Sec. 2, Shih-Pai Rd., Taipei 112, Taiwan

    Lung-Chi Wu & Yun-Ting Chang

Authors
  1. Lung-Chi Wu
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  2. Pei-Lun Sun
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  3. Yun-Ting Chang
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Correspondence to Yun-Ting Chang.

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Wu, LC., Sun, PL. & Chang, YT. Extensive Deep Dermatophytosis Cause by Trichophyton rubrum in a Patient with Liver Cirrhosis and Chronic Renal Failure. Mycopathologia 176, 457–462 (2013). https://doi.org/10.1007/s11046-013-9696-2

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  • DOI: https://doi.org/10.1007/s11046-013-9696-2

Keywords

  • Extensive
  • Deep
  • Dermatophytosis
  • Trichophyton rubrum
  • Liver cirrhosis
  • Chronic renal failure