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Rare Arthroconidial Fungi in Clinical Samples: Scytalidium cuboideum and Arthropsis hispanica

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Abstract

We report the presence of the two arthroconidial anamorphic fungi, Scytalidium cuboideum and Arthropsis hispanica, in clinical samples from the USA. Both fungi were morphologically and molecularly identified. The antifungal susceptibility of four isolates of A. hispanica and five of S. cuboideum to eight antifungal drugs is provided.

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References

  1. Miceli MH, Lee SA. Emerging moulds: epidemiological trends and antifungal resistance. Mycoses. 2011;54:666–78.

    Article  Google Scholar 

  2. De Hoog GS, Guarro J, Gené J, Figueras MJ. Atlas of clinical fungi. CD-ROM version 3.1, CBS-KNAW Fungal Biodiversity Centre, Utrecht. 2011.

  3. Balajee SA, et al. Sequence-based identification of Aspergillus, Fusarium, and Mucorales species in the clinical mycology laboratory: where are we and where should we go from here? J Clin Microbiol. 2009;47:877–84.

    Article  PubMed  CAS  Google Scholar 

  4. Samson RA, Varga J. What is a species in Aspergillus? Med Mycol. 2009;47(Suppl 1):S13–20.

    Article  PubMed  CAS  Google Scholar 

  5. Tavanti A, Davidson AD, Gow NA, Maiden M, Odds F. Candida orthopsilosis and Candida metapsilosis sp. nov. to replace Candida parapsilosis groups II and III. J Clin Microbiol. 2005;43:284–92.

    Article  PubMed  CAS  Google Scholar 

  6. White TJ, Bruns T, Lee S, Taylor J. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In: Innis MA, Gelfand DH, Sninsky JJ, White TJ, editors. PCR protocols: a guide to the methods and applications. New York: Academic Press; 1990. p. 315–22.

    Google Scholar 

  7. Marimon R, Gené J, Cano J, Trilles L, Dos Santos M, Guarro J. Molecular phylogeny of Sporothrix schenckii. J Clin Microbiol. 2006;44:3251–6.

    Article  PubMed  CAS  Google Scholar 

  8. Marimon R, Serena C, Gené J, Cano J, Guarro J. In vitro antifungal susceptibilities of five species of Sporothrix. Antimicrob Agents Chemother. 2008;52:732–4.

    Article  PubMed  CAS  Google Scholar 

  9. O’Donnell K. Phylogeny of the Nectria haematococcaFusarium solani species complex. Mycologia. 2000;92:919–38.

    Article  Google Scholar 

  10. Alastruey-Izquierdo A, Cuenca-Estrella M, Monzón A, Mellado E, Rodríguez-Tudela JL. Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods. J Antimicrob Chemother. 2008;61:805–9.

    Article  PubMed  CAS  Google Scholar 

  11. Azor M, Gené J, Cano J, Sutton DA, Fothergill AW, Rinaldi MG, Guarro J. In vitro antifungal susceptibility and molecular characterization of clinical isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum. Antimicrob Agents Chemother. 2008;5:2228–31.

    Article  Google Scholar 

  12. O’Donnell K, Sutton D, Fothergill A, et al. Molecular phylogenetic diversity, multilocus haplotype nomenclature, and in vitro antifungal resistance within the Fusarium solani species complex. J Clin Microbiol. 2008;46:2477–90.

    Article  PubMed  Google Scholar 

  13. Sigler L, Carmichael JW. Taxonomy of Malbranchea and some other Hyphomycetes with arthroconidia. Mycotaxon. 1976;4:349–488.

    Google Scholar 

  14. Sigler L, Carmichael JW. Redisposition of some fungi referred to Oidium microspermum and a review of Arthrographis. Mycotaxon. 1983;18:495–507.

    Google Scholar 

  15. Ulfig K, Gené J, Guarro J. Studies on keratinophilic fungi. VI. A new Arthropsis (Fungi Imperfecti) from marine sediments. Mycotaxon. 1995;54:281–6.

    Google Scholar 

  16. O’Donnell K. Fusarium and its near relatives. In: Reynolds DR, Taylor JW, editors. The fungal holomorph: mitotic, meiotic and pleomorphic speciation in fungal systematics. Wallingford: CAB International; 1993. p. 225–33.

    Google Scholar 

  17. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The Clustal X Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997;25:4876–82.

    Article  PubMed  CAS  Google Scholar 

  18. Nicholas KB, Nicholas HB, Deerfield DWII. GeneDoc: analysis and visualization of genetic variation. EMBnet News. 1997;4:1–4.

    Google Scholar 

  19. Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi. Approved standard. 2nd ed. Wayne: Document M38–A2. Clinical and Laboratory Standards Institute; 2008.

    Google Scholar 

  20. Udagawa S, Tominaga K, Hamaoka T. Scytalidium japonicum, a new species, the causal agent of cattle bronchiolitis. Mycotaxon. 1986;25:279–86.

    Google Scholar 

  21. Iwatsu T, Udagawa S, Hatai K. Scytalidium infestans sp. nov., isolated from striped jack (Pseudocaranx dentex) as a causal agent of systemic mycosis. Trans Mycol Soc Jpn. 1990;31:389–97.

    Google Scholar 

  22. Da Silva C, Dias A, Heins E, Cucé L, Benatti C, Spina R, Takahashi N, Santos R, Hernandez G. Onychomycosis caused by Scytalidium dimidiatum. Report of two cases. Review of the taxonomy of the synanamorph and anamorph forms of this coelomycete. Rev Inst Med Trop Sao Paulo. 1999;41:319–23.

    Google Scholar 

  23. Lacroix C, Feuilhade de Chauvin M. In vitro activity of amphotericin B, itraconazole, voriconazole, posaconazole, caspofungin and terbinafine against Scytalidium dimidiatum and Scytalidium hyalinum clinical isolates. J Antimicrob Chemother. 2008;61:835–7.

    Article  PubMed  CAS  Google Scholar 

  24. Madrid H, Ruiz M, Cano J, Stchigel A, Orofino R, Guarro J. Genotyping and in vitro antifungal susceptibility of Neoscytalidium dimidiatum isolates from different origins. Int J Antimicrob Agents. 2009;34:351–4.

    Article  PubMed  CAS  Google Scholar 

  25. Crous PW, Slippers B, Wingfield MJ, Rheeder J, Marasas WF, Philips AJ, et al. Phylogenetic lineages in the Botryosphaeriaceae. Stud Mycol. 2006;55:235–53.

    Article  PubMed  Google Scholar 

  26. Saccardo PA. Fungi boreali-americani. Michelia. 1882;2:564–82.

    Google Scholar 

  27. Kang HJ, Sigler L, Lee J, Gibas CF, Yun SH, Lee YW. Xylogone ganodermophthora sp. nov., an ascomycetous pathogen causing yellow rot on cultivated mushroom Ganoderma lucidum in Korea. Mycologia. 2010;102:1167–84.

    Article  PubMed  CAS  Google Scholar 

  28. Sigler L, Dunn MT, Carmichael JW. Arthrocristula and Arthropsis, two new hyphomycetes with dematiaceous arthroconidia. Mycotaxon. 1982;15:409–19.

    Google Scholar 

  29. Oorschot C, De Hoog GS. Some Hyphomycetes with thallic conidia. Mycotaxon. 1984;20:129–32.

    Google Scholar 

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Acknowledgments

This study was supported by the Spanish Ministerio de Ciencia e Innovación, grants CGL 2009-08698/BOS and CGL 2011-27185/BOS.

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Correspondence to Josepa Gené.

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Giraldo, A., Sutton, D.A., Gené, J. et al. Rare Arthroconidial Fungi in Clinical Samples: Scytalidium cuboideum and Arthropsis hispanica . Mycopathologia 175, 115–121 (2013). https://doi.org/10.1007/s11046-012-9590-3

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  • DOI: https://doi.org/10.1007/s11046-012-9590-3

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