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Evaluation of Pathological Effects in Broilers During Fumonisins and Clays Exposure

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Abstract

This study was conducted to evaluate the possible protector effect of bentonite and zeolite in Bovans chicks fed a diet containing 59 mg kg−1 of fumonisin B1 (FB1) during 3 weeks. A total of 200 one-day-old male chicks were treated varying the amount of bentonite and zeolite. Chick weight was registered weekly. At the end of the experiment, all the chicks were killed, and the livers were analyzed for gross examination and histopathological changes. Plasmatic activity of alanine amino transferase and aspartate amino transferase (AST) were also determined. Sphinganine and the sphinganine-to-sphingosine ratio in serum were evaluated. Both, bentonite and zeolite showed a protector effect against FB1 adsorption in the digestive tract of chicks. Chicks fed with FB1-contaminated feed, amended either with zeolite or bentonite, were heavier, and no macroscopic lesions were observed in the livers. AST activity might be considered as an indicator for FB1 exposition because AST levels were affected when only FB1 was present in the basal diet. These results indicate that both, zeolite and bentonite can be added into feed to diminish the effects of FB1.

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Authors and Affiliations

  1. Department of Food Research and Graduate Program, University of Sonora, Blvd, Luis Encinas y Rosales s/n. Col. Centro, CP 83000, Hermosillo, Sonora, Mexico

    Jesús Enrique Vizcarra-Olvera, Armando Burgos-Hernández, Norma Violeta Parra-Vergara, Francisco Javier Cinco-Moroyoqui, Eber Addi Quintana-Obregón & Mario Onofre Cortez-Rocha

  2. CIAD (Research Center in Food and Development), Carretera a la Victoria, Km. 0.6, Hermosillo, Sonora, Mexico

    Humberto Astiazarán-García

  3. Department of Chemical-Biological Sciences, University of Sonora, P.O. Box 1658, CP 83000, Hermosillo, Sonora, Mexico

    Reyna Isabel Sánchez-Mariñez

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  1. Jesús Enrique Vizcarra-Olvera
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Correspondence to Mario Onofre Cortez-Rocha.

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Vizcarra-Olvera, J.E., Astiazarán-García, H., Burgos-Hernández, A. et al. Evaluation of Pathological Effects in Broilers During Fumonisins and Clays Exposure. Mycopathologia 174, 247–254 (2012). https://doi.org/10.1007/s11046-012-9534-y

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  • DOI: https://doi.org/10.1007/s11046-012-9534-y

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