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Paracoccidioidal Infection in HIV Patients at an Endemic Area of Paracoccidioidomycosis in Brazil

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Abstract

The association between paracoccidioidomycosis (PCM) and AIDS is relatively rare in contrast to the higher incidence of other systemic mycosis. The explanation may be that AIDS is still predominantly an urban disease, and the PCM is endemic in Latin American rural areas. The aim of this study was to detect the prevalence of Paracoccidioides brasiliensis infection in HIV-positive patients at an endemic area of paracoccidioidomycosis in Brazil. Skin test with purified 43 kD glycoprotein (gp43) was performed in 90 HIV/AIDS patients. The prevalence found was 12.2% and it may be even greater, considering that HIV/AIDS patients may not respond to the intradermal test, which depends on cellular immunity for its positivity.

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Acknowledgments

The study was supported by Departamento de Ciência e Tecnologia do Ministério da Saúde (DECIT MS/Brazil- UNESCO) and Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP).

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Authors and Affiliations

  1. Universidade Anhanguera Uniderp, Rua Ceará, 333. Bairro Miguel Couto, Campo Grande, MS, CEP 79003-010, Brazil

    Elaine Cristina Fernandes Baez Sarti

  2. Universidade Federal de Mato Grosso do Sul, Rua Marques de Pombal, 1889 apt 3, Bloco A, Campo Grande, MS, CEP 79041-080, Brazil

    Sandra Maria do Valle Leone de Oliveira

  3. Rua das Paineiras, 68, Campo Grande, MS, CEP 79010-070, Brazil

    Liara Ferreira dos Santos

  4. Universidade Federal de São Paulo, Rua Botucatu, 862, Vila Clementino, São Paulo, SP, CEP 04023-062, Brazil

    Zoilo Pires de Camargo

  5. Universidade Federal de Mato Grosso do Sul, Rua das Paineiras, 68, Bairro São Francisco, Campo Grande, MS, CEP 79010-070, Brazil

    Anamaria Mello Miranda Paniago

Authors
  1. Elaine Cristina Fernandes Baez Sarti
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  2. Sandra Maria do Valle Leone de Oliveira
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  3. Liara Ferreira dos Santos
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  4. Zoilo Pires de Camargo
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  5. Anamaria Mello Miranda Paniago
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Correspondence to Anamaria Mello Miranda Paniago.

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Sarti, E.C.F.B., de Oliveira, S.M.V.L., dos Santos, L.F. et al. Paracoccidioidal Infection in HIV Patients at an Endemic Area of Paracoccidioidomycosis in Brazil. Mycopathologia 173, 145–149 (2012). https://doi.org/10.1007/s11046-011-9495-6

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  • DOI: https://doi.org/10.1007/s11046-011-9495-6

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