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Fusarium toxins of the scirpentriol subgroup: a review

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Abstract

Scirpentriol and its seven acetylated derivatives comprise a family of type-A trichothecene toxins produced by several species of Fusarium fungi. Out of this group 4,15-diacetoxyscirpenol has attracted most attention. It elicits toxic responses in several species and was detected in a variety of substrates. Out of the three possible monoacetylated derivatives 15-monoacetoxyscirpenol and the parent alcohol scirpentriol received some attention, whereas the remaining members of the family were mentioned in few reports. The present review deals with the structure, biosynthesis, analysis and toxicity of scirpentriol toxins. Formation by Fusarium species as well as culture conditions used for toxigenicity studies are reviewed; data about the natural occurrence of scirpentriol toxins in different cereal types, cereal associated products as well as in non-grain matrices including potato and soya bean are reported. Basing on literature reports about the toxicity of scirpentriol toxins an attempt is made to summarise the state of knowledge for risk evaluation for human and animal health.

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Abbreviations

DAS:

Diacetoxyscirpenol

DON:

Deoxynivalenol

FUS-X:

Fusarenon-X

F. :

Fusarium

HT-2:

HT-2 toxin

MAS:

Monoacetoxyscirpenol

NIV:

Nivalenol

SCIRP:

Scirpentriol

TAS:

3,4,15-Triacetoxyscirpenol

T-2:

T-2 toxin

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Schollenberger, M., Drochner, W. & Müller, HM. Fusarium toxins of the scirpentriol subgroup: a review. Mycopathologia 164, 101–118 (2007). https://doi.org/10.1007/s11046-007-9036-5

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