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Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand

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Abstract

Nocardia cyriacigeorgica is a recently described species. During routine diagnostic testing of 121 clinical isolates, we found that about one fourth of the strains from Japan (19 isolates) and Thailand (8 isolates), which were identified in our laboratories as N. asteroides, in fact belong to N. cyriacigeorgica. To our knowledge, this is the first report of infection due to N. cyriacigeorgica in Japan and Thailand, and the third report of infection anywhere in the world. Although N. cyriacigeorgica is usually differentiated from other Nocardia species by utilization of glucose and gluconate, we found that it can also be differentiated by a characteristic synergistic effect between imipenem (IPM) and tobramycin (TOB).

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Authors and Affiliations

  1. Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8673, Japan

    Akiko Kageyama, Yasutaka Hoshino, Katsukiyo Yazawa, Nobuyoshi Takeshita, Satoshi Maki & Yuzuru Mikami

  2. Division of Mycology, National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand

    Natteewan Poonwan

Authors
  1. Akiko Kageyama
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  2. Yasutaka Hoshino
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  3. Katsukiyo Yazawa
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  4. Natteewan Poonwan
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  5. Nobuyoshi Takeshita
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  6. Satoshi Maki
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  7. Yuzuru Mikami
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Correspondence to Yuzuru Mikami.

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Kageyama, A., Hoshino, Y., Yazawa, K. et al. Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand. Mycopathologia 160, 15–19 (2005). https://doi.org/10.1007/s11046-005-3050-2

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  • DOI: https://doi.org/10.1007/s11046-005-3050-2

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