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Feasibility study of foldscope microscope for selected mammalian endocrine glands

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Foldscope is a low cost, an origami-based optical microscope. It is extremely portable, durable, and can be assembled and constructed in minutes, achieving a magnification of 140X and a resolution of 2 μm. The objective of the present study is to evaluate the feasibility of foldscope by using mobile phone-based microscopy for class room study by selecting slides of mammalian endocrine glands (adrenal, thyroid, ovary, testis and pancreas), and to compare with the conventional microscope in the laboratory facility. Mobile phones were connected with the foldscope using a cassette and magnetic coupler to take images of the histology samples. The image acquired from both sources were edited further and put together for comparison. It was found that tissue sections of mammalian endocrine glands observed under foldscope were comparable to conventional light microscope images. The overall study of the images by the foldscope showed its potential use for classroom demonstration. It could also be stated that mobile phone-based portable microscopy with foldscope is feasible for histological sample investigations, especially in Limited-Resource Institutions.

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Data availability

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.


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The authors acknowledge Department of Biotechnology (DBT), Government of India, New Delhi for providing financial support and Foldscopes for carrying out this research work to PPP and VKR.


PPP and VKR received the funding from Department of Biotechnology (BT/IN/Indo-US/Foldscope/39/2015), New Delhi under Foldscope project scheme.

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Correspondence to Vikas Kumar Roy, Rajesh Kumar Kharwar or Pranay Punj Pankaj.

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Jamir, A., Longkumer, S., Roy, V.K. et al. Feasibility study of foldscope microscope for selected mammalian endocrine glands. Multimed Tools Appl 83, 16197–16203 (2024).

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