Abstract
The system proposed is oriented to evaluate the pain perceived by the user under a high controlled virtual reality environment (VR). A VR system is an implementation of a virtual world that the user perceives as the real one. The sensation of immersion affects the stimulus (visual, acoustic and haptic) perceived by the user and it is able to promote change in the brainwaves power and produce an activation of Autonomic Nervous System (ANS). The Electro-Dermal Activity (EDA) allow measuring the electrical properties of the skin by the sweat activity. This work proposes a VR environment combined with binaural beats (binaural sounds) and visual stimulus to evaluate the perception that the user has and comparing their sensation with real physiological data. It is believed that the use of different binaural beats in a long period of time can help patients to induce a relaxation state (mood) and consequently modulate the perception to pain. In this study we show two experiments. The first one applies 8 types of acoustic stimulus (4 binaural and 4 monaural) in a standard simple VR scenario and we propose the end users to select the experimented feeling they felt in any case, in parallel using the Empatica wristband we contrast the subjective users answers with physiological values given by the device. In the second experiment, an immersive environment based on the whole VR application is proposed for control and real users to evaluate chronic pain. The users are immersed in three VR equal scenarios but with random sound stimulation. With the results obtained, we can conclude that binaural beats work better than non-binaural beats if we talk about relaxation and meditation.
Similar content being viewed by others
References
Austin DW, Abbott JAM, Carbis C (2008) The use of virtual reality hypnosis with two cases of autism spectrum disorder: a feasibility study. Contemp Hypn 25(2):102–109
Barragán B, Parra C, Contreras M, Pulido P (2003) Manejo de la ansiedad mediante la combinación de desensibilización sistemática con relajación muscular, relajación autógena y biorretroalimentación. Suma Psicológica 10(2):135–152
Berger TW, Chapin JK, Gerhardt GA, McFarland DJ, Principe JC, Soussou WV, Taylor DM, Tresco PA (2009) Brain-Computer Interfaces: An international assessment of research and development trends. Springer. ISBN: 978-4020-8704-2
Braithwaite J, Watson D, et al. A Guide for Analysing Electrodermal Activity (EDA) & Skin Conductance Responses (SCRs) for Psychological Experiments. Technical Report. Selective Attention & Awareness Laboratory (SAAL), University of Birmingham, UK.
Chaieb L, Wilpert EC, Reber TP, Fell J (2015) Auditory beat stimulation and its effects on cognition and mood states. Psychiatry, 12 May 2015 | https://doi.org/10.3389/fpsyt.2015.00070
Cvetkovic D, Djuwari D, Cosic I (Australia) 2004 The Induced Rhythmic Oscillations of Neural Activity in the Human Brain. Proceeding (417) Biomedical Engineering
Dahlquist LM, Weiss KE, Dillinger Clendaniel L, Law EF, Ackerman CS, McKenna KD (2008) Effects of videogame distraction using a virtual reality type head-mounted display helmet on cold pressor pain in children. J Pediatr Psychol 34(5):574–584
Dubé A, Duquette M, Roy M et al (2009) Brain activity associated with the electrodermal reactivity to acute heat pain. NeuroImage 45:169–180
Fran L-C, Carles E (2017) Binaural Beat: A Failure to Enhance EEG Power and Emotional Arousal. Frontiers in Human Neuroscience. Vol 11, pp. 557. doi.org/10.3389/fnhum.2017.00557. ISSN=1662-5161
Gallegos X, Torres Torrija FJ (1983). Biorretroalimentación de la respuesta galvánica de la piel y entrenamiento en relajación: un estudio piloto. Revista latinoamericana de psicología, 15(1-2)
Gao X, Cao H, Ming D et al (December 2014) Analysis of EEG activity in response to binaural beats with different frequencies. Int J Psychophysiol 94(3):399–406. https://doi.org/10.1016/j.ijpsycho.2014.10.010
Garrett B, Taverner T, McDade P (2017) Virtual Reality as an Adjunct Home Therapy in Chronic Pain Management: An Exploratory Study. JMIR medical informatics, 5(2)
Geršak G, Lu H, Guna J (2018) Effect of VR technology matureness on VR sickness. Multimedia Tools and Applications, 1/12/2018. Springer Science+Business Media, LLC, part of Springer Nature. https://doi.org/10.1007/s11042-018-6969-2
Gupta A, Ramdinmawii E, Mittal VK (2017) Significance of Alpha Brainwaves in Meditation examined from the study of Binaural Beats. Indian Institute of Information Technology, Chittor, Sricity, A. P., India. July
Guruprasath G, Gnanavel S (2015) Effect of continuous and short burst binaural beats on EEG signals. SRM University, Tamil Nadu, India
Hoffman HG, Richards T, Coda B, Richards A, Sharar SR (2003) The illusion of presence in immersive virtual reality during an fMRI brain scan. CyberPsychol Behav 6(2):127–131
Hoffman HG, Richards TL, Bills AR, Van Oostrom T, Magula J, Seibel EJ, Sharar SR (2006) Using fMRI to study the neural correlates of virtual reality analgesia. CNS spectr 11(1):45–51
Jacobs KW, Hustmyer FE Jr. (1974) Effects of Four Psychological Primary Colors on GSR, Heart Rate and Respiration Rate. Perceptual and Motor Skills. First Published June 1, Research Article. https://doi.org/10.2466/pms.1974.38.3.763. Volume: 38 issue: 3, page(s): 763-766.
Jirakittayakorn N, Wongsawat Y (2017) Brain Responses to a 6-Hz Binaural Beat: Effects on General Theta Rhythm and Frontal Midline Theta Activity Front. Neuroscience. 28 June| https://doi.org/10.3389/fnins.2017.00365. ISSN=1662-453X
Knight WE, Rickard NS (2001) Relaxing music prevents stress-induced increases in subjective anxiety, systolic blood pressure, and heart rate in healthy males and females. J Music Ther 38(4):254–272
Koreographer – Unity Asset: https:// http://koreographer.com
Kumar Singh S, Tiwari S, Imam Abidi A, Singh A (2017) Prediction of pain intensity using multimedia data. 7/7/2017. Multimed Tools Appl 76:19317–19342. https://doi.org/10.1007/s11042-017-4718-6
López FJP, Amengual E (2017) Combining EEG and Serious Games for Attention Assessment of Children with Cerebral Palsy. Converging Clinical and Engineering Research on Neuororehabilitation II. pp. 395-399. https://doi.org/10.1007/978-3-319-46669-9_66. Oct
Malloy KM, Milling LS (2010) The effectiveness of virtual reality distraction for pain reduction: a systematic review. Clin Psychol Rev 30(8):1011–1018
McNair DM, Heuchert JP (2011) Profile of Mood States, 2nd EditionTM (POMS 2TM), JvR Psychometrics Assessment Catalogue
Mercado J, Espinosa-Curiel I, Escobedo L, Tentori M (2018) Developing and evaluating a BCI video game for neurofeedback training: the case of autism, Multimedia Tools and Applications.19/11/2018. Springer Science+Business Media, LLC, part of Springer Nature. https://doi.org/10.1007/s11042-018-6916-2
Miró J, Nieto R, Huguet A (2007) Realidad virtual y manejo del dolor. Cuadernos de Medicina Psicosomática 82:52–64
Oculus Rift – Virtual reality system: https://www.oculus.com/rift/
OculusAvatarSDK [ https://developer.oculus.com/documentation/avatarsdk/latest/concepts/avatars-sdk-intro/ ]. Last Visit: 11/03/2019.
On FR, Jailani R, Norhazman H, Mohamad Zaini N (2013) Binaural Beat Effect on Brainwaves based on EEG. March
Perales FJ, Sánchez M, Riera L, Ramis S (2018) A Pilot Study: VR and Binaural Sounds for Mood Management. 22 International Conference Information Visualization, 10 - 13 July, Università degli Studi di Salerno, Salerno, Italy. IEEE Proceedings
Pfaff HU (2014) Psychophysiological reactivity to auditory Binaural Beats stimulation in the alpha and theta EEG brain-wave frequency bands: A randomized, double–blind and placebo-controlled study in human healthy young adult subjects. UAM. Departamento de Psicología Biológica y de la Salud. http://hdl.handle.net/10486/663948
Sanei S (2013) Adaptive Processing of Brain Signals. John Wiley & Sons, Ltd. ISBN: 9780470686133. https://doi.org/10.1002/9781118622162
Spyridonis F, Hansen J, Grønli TM, Ghinea G (2014) PainDroid: an android-based virtual reality application for pain assessment. 10/1/2013. Multimed Tools Appl 72:191–206. DOI https://doi.org/10.1007/s11042-013-1358-3
Sturmey P, Newton T, Ghadiali EJ (1988) Psychometric properties of the Pain Assessment Questionnaire. Br J Clin Psychol 27(Pt 2):183–184
Tageldeen MK, Elamvazuthi I, Perumal N, Ganesan T (2017) A Virtual Reality based Serious Game for Rehabilitation of Arm. Department of Electrical & Electronic Engineering, Universiti Teknologi PETRONAS, and Perak, Malaysia. December
The E4 wristband, https://www.empatica.com/
Unity – Game Engine: https://unity3d.com
Vargas-Orjuela M, Uribe-Quevedo A, Rojas D, Kapralos B, Perez-Gutierrez B (2017) A Mobile Immersive Virtual Reality Cardiac Auscultation App. Universidad Militar Nueva Granada, Bogota, Colombia. October
Wahbeh H, Calabrese C, Zwickey H, Zajdel D (2007) Binaural beat technology in humans: a pilot study to assess neuropsychologic, physiologic, and electroencephalographic effects. J Altern Complement Med 13(2):199–206
Wiederhold BK, Anal K, Sulea C, Wiederhold MD (2014) Virtual reality as a distraction technique in chronic pain patients. Cyberpsychol Behav Soc Netw 17(6):346–352
Wiederhold BK, Miller IT, Wiederhold MD (2017) Using Virtual Reality to Mobilize Health Care. IEEE Consumer Electronics Magazine. December
Wolitzky K, Fivush R, Zimand E, Hodges L, Rothbaum BO (2005) Effectiveness of virtual reality distraction during a painful medical procedure in pediatric oncology patients. Psychol Health 20(6):817–824
Acknowledgments
We acknowledge the Ministerio de Economía, Industria y Competitividad (MINECO), the Agencia Estatal de Investigación (AEI) and the European Regional Development Funds (ERDF, EU) for its support to the project TIN2015-67149-C3-2-R (MINECO/AEI/ERDF, EU). We also acknowledge the program «Salvador de Madariaga» (Estancias de profesores e investigadores senior en centros extranjeros) from Ministerio de educación, cultura y deporte (Solicitud PRX16/00234). The third author is beneficited by the FPI/1828/2015 fellowship from the “Conselleria d’Educació, Cultura i Universitats del Govern de les Illes Balears Also I would like to give many thanks to Miguel Sanchez from previous work done in this Project.
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Perales, F.J., Riera, L., Ramis, S. et al. Evaluation of a VR system for Pain Management using binaural acoustic stimulation. Multimed Tools Appl 78, 32869–32890 (2019). https://doi.org/10.1007/s11042-019-07953-y
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11042-019-07953-y