Multimedia Tools and Applications

, Volume 76, Issue 8, pp 10761–10775 | Cite as

Multi-view feature selection and classification for Alzheimer’s Disease diagnosis

  • Mingxing Zhang
  • Yang Yang
  • Fumin Shen
  • Hanwang Zhang
  • Yuan Wang


In our present society, Alzheimer’s disease (AD) is the most common dementia form in elderly people and has been a big social health problem worldwide. In this paper, we propose a novel multi-view classification method based on l 2,p -norm regularization for Alzheimer’s Disease (AD) diagnosis. Unlike the previous l 2,1 -norm regularized methods using concatenated multi-view features, we further consider the intra-structure and inter-structure relations between features of different views and use a more flexible l 2,p -norm regularization in our objective function. We also proposed a more suitable loss function to measure the loss between labels and predicted values for classification task. It experimentally demonstrated that this method enhances the performance of disease status classification, comparing to the state-of-the-art methods.


Alzheimer’s Disease (AD) Social health Multi-view classification l2,p-norm l2,l-norm 



This work was supported in part by the National Nature Science Foundation of China under Project 61572108.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Mingxing Zhang
    • 1
  • Yang Yang
    • 1
  • Fumin Shen
    • 1
  • Hanwang Zhang
    • 2
  • Yuan Wang
    • 2
  1. 1.University of Electronic Science and Technology of ChinaChengduChina
  2. 2.National University of SingaporeSingaporeSingapore

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