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Molecular Biology Reports

, Volume 46, Issue 2, pp 2541–2546 | Cite as

Forensic characteristics and phylogenetic structure of Eastern Chinese Han populations residing along the Yangtze Basin revealed by 19 autosomal STR loci

  • Ruiyang Tao
  • Shouyu Wang
  • Ming Jin
  • Yanting Liu
  • Jiashuo Zhang
  • Suhua ZhangEmail author
  • Chengtao LiEmail author
Short Communication
  • 56 Downloads

Abstract

In present study, forensic parameters based on the population data of nineteen autosomal short tandem repeats (STRs) loci were estimated in Chinese Han populations from three riverfront areas of Yangtze Basin in Eastern China. The combined power of discrimination (CPD) were 0.9999999999999999999999883, 0.9999999999999999999999846 and 0.9999999999999999999999863, respectively. The combined power of exclusion (CPE) were 0.999999992248957, 0.999999989800400 and 0.999999989799819, respectively. Furthermore, the genetic relationships among our studied populations and 32 previously investigated populations residing in other areas of China were also analyzed based on pairwise genetic distances (FST). The multidimensional scaling (MDS) plot and phylogenetic tree indicated that our studied populations were majorly clustered with the Han populations along the Yangtze Basin and populations to the north of it. In summary, our results supported that the 19 autosomal STR loci, which were polymorphic and informative in forensic identification, could also be applied in population genetics studies.

Keywords

Forensic genetics Short tandem repeat Yangtze Basin Eastern Chinese Han Phylogenetic relationship 

Notes

Acknowledgements

This study was supported by grants from the National Key R&D Program of China (Grant No. 2016YFC0800703), Standard Program of Shanghai Municipality (Grant Nos. 16DZ0501600, 18DZ1200300), Public Interest Research Grant Programs of National Research Institutes (Grant No. GY2017D-2) and the National Natural Science Foundation (Grant Nos. 81625013, 81772028). The funders had no role in study design, data analysis, publishing decisions, or manuscript preparation.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

11033_2019_4633_MOESM1_ESM.xlsx (50 kb)
Supplemental Tables 1 to 5—Supplementary material 1 (XLSX 50 KB)
11033_2019_4633_MOESM2_ESM.tif (28 mb)
Fig. S1. A heatmap illustrating the allele distribution of our studied populations and other 22 previously reported Han populations. The color gradually turns from white to red as the allelic frequency increases. Hierarchical clustering based on the Euclidean distances was also performed on each shared locus—Supplementary material 2 (TIF 28658 KB)
11033_2019_4633_MOESM3_ESM.tif (9.9 mb)
Fig. S2. A map showing the geographical distribution of our studied populations and another 32 previously published Chinese populations applied in this comparison, including 22 Han populations and 10 ethnic minorities. The three studied populations were underlined—Supplementary material 3 (TIF 10113 KB)

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic MedicineSichuan UniversityChengduPeople’s Republic of China
  2. 2.Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic SciencesMinistry of Justice, P.R. ChinaShanghaiPeople’s Republic of China
  3. 3.Public Security Bureau of ChangzhouChangzhouPeople’s Republic of China
  4. 4.Jiangsu Province Hospital and Nanjing Medical University First Affiliated HospitalNanjingPeople’s Republic of China
  5. 5.Department of Forensic ScienceMedical School of Soochow UniversitySuzhouPeople’s Republic of China

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