Molecular Biology Reports

, Volume 45, Issue 6, pp 2935–2940 | Cite as

Monoclonal antibodies in cancer immunotherapy

  • Ilgin Kimiz-Gebologlu
  • Sultan Gulce-Iz
  • Cigir Biray-AvciEmail author


Nowadays, in cancer treatments, immunotherapy which can be classified as a cancer type specific therapy is more popular than non-specific therapy methods such as surgery, radiotherapy and chemotherapy. The main aim of immunotherapy is to enable patients’ immune system to target cancer cells and destroy them. The mainly used treatment methods in cancer immunotherapy are cancer vaccines, adoptive cell therapy, cytokines and monoclonal antibodies. In this review, we discuss the immunotherapy approaches, especially monoclonal antibodies which are mostly used in cancer immunotherapy in clinical applications.


Immunotherapy Monoclonal antibody Cancer Treatment 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  1. 1.Bioengineering Graduate Programme, Institute of Natural & Applied SciencesEge UniversityIzmirTurkey
  2. 2.Department of Bioengineering, Faculty of EngineeringEge UniversityIzmirTurkey
  3. 3.Biomedical Technologies Graduate Programme, Institute of Natural & Applied SciencesEge UniversityIzmirTurkey
  4. 4.Department of Medical Biology, Medical SchoolEge UniversityIzmirTurkey

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