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Molecular Biology Reports

, Volume 41, Issue 4, pp 2559–2569 | Cite as

X-Chromosome STR markers data in a Cabo Verde immigrant population of Lisboa

  • Heloísa Afonso CostaEmail author
  • Paulo Morais
  • Cláudia Vieira da Silva
  • Sara Matos
  • Rodolfo Marques Santos
  • Rosa Espinheira
  • Jorge Costa Santos
  • António Amorim
Article

Abstract

Population genetic data of 12 X chromosomal short tandem repeats markers (DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, DXS7132, DXS7423, DXS8378 and HPRTB) were analysed in 54 females and 95 males of an immigrant population from Cabo Verde living in Lisboa. The obtained results for forensic statistical parameters such as observed heterozigosity, polymorphism information content, power of discrimination and mean exclusion chance, based on single allele frequencies, reveal that this multiplex system is highly informative and can represent an important tool for genetic identification purposes in the immigrant population of Cabo Verde. Since the studied short tandem repeats genetic markers are distributed on four linkage groups, that can provide independent genotype information, we studied those groups as haploytes. The forensic efficiency parameters for the linked groups were all higher than 0.97, with linkage group I being the most polymorphic and linkage group III the less informative.

Keywords

X-Chromosome STR markers Genetic population Forensic genetics Cabo Verde 

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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Heloísa Afonso Costa
    • 1
    • 6
    Email author
  • Paulo Morais
    • 1
    • 5
  • Cláudia Vieira da Silva
    • 1
    • 6
  • Sara Matos
    • 1
    • 5
  • Rodolfo Marques Santos
    • 1
    • 6
  • Rosa Espinheira
    • 1
    • 6
  • Jorge Costa Santos
    • 2
    • 3
    • 6
  • António Amorim
    • 1
    • 4
    • 6
  1. 1.Serviço de Genética e Biologia ForensesInstituto Nacional de Medicina Legal e Ciências Forenses I.P.LisboaPortugal
  2. 2.Serviço de Clínica ForenseInstituto Nacional de Medicina Legal e Ciências ForensesLisbonPortugal
  3. 3.Medicina Legal e Ciências Forenses, Faculdade de MedicinaUniversidade de LisboaLisbonPortugal
  4. 4.Ciências Forenses e CriminaisInstituto Superior de Ciências de Saúde Egas MonizCaparicaPortugal
  5. 5.Biologia Molecular em SaúdeEscola Superior de Saúde Egas MonizAlmadaPortugal
  6. 6.CENCIFOR - Centro de Ciências ForensesCoimbraPortugal

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