Abstract
Several options are available to the scientific community for genetic map construction but few are simple to install and use. Available programs either lack intuitive interface or are commercial, expensive for many laboratories. We present MapDisto, a free, user-friendly and powerful program for constructing genetic maps from experimental segregating populations. MapDisto is freely available at http://mapdisto.free.fr/DL/. Current version: 1.7.5.
References
Allard RW (1956) Formulas and tables to facilitate the calculation of recombination values in heredity. Hilgardia 24:235–278
Bailey NTJ (1949) The estimation of linkage with differential viability, II and III. Heredity 3:220–228
Garavito A, Guyot R, Lozano J, Gavory F, Samain S, Panaud O, Tohme J, Ghesquiere A, Lorieux M (2010) A genetic model for the female sterility barrier between Asian and African cultivated rice species. Genetics 185(4):1425–1440
Holloway J, Knapp SJ (1994) Gmendel 3.0 users guide. http://www.css.orst.edu/G-Mendel/Default.htm
Joehanes R, Nelson JC (2008) QGene 4.0, an extensible Java QTL-analysis platform. Bioinformatics 24:2788–2789
Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newburg L (1987) Mapmaker: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1:174–181
Lorieux M, Goffinet B, Perrier X, González de León D, Lanaud C (1995a) Maximum-likelihood models for mapping genetic markers showing segregation distortion. 1. Backcross populations. Theor Appl Genet 90:73–80
Lorieux M, Perrier X, Goffinet B, Lanaud C, González de León D (1995b) Maximum-likelihood models for mapping genetic markers showing segregation distortion. 2. F2 populations. Theor Appl Genet 90:81–89
Manly KF, Cudmore RH, Meer JM (2001) Map manager QTX, cross-platform software for genetic mapping. Mamm Genome 12(12):930–932
Mester DI, Ronin YI, Minkov D, Nevo E, Korol AB (2003) Constructing large scale genetic maps using an evolutionary strategy algorithm. Genetics 165:2269–2282
Rebai A, Goffinet B, Mangin B (1995) Comparing power of different methods for QTL detection. Biometrics 51(1):87–99
Schiex T, Gaspin C (1997) CARTHAGENE: constructing and joining maximum likelihood genetic maps. In: Proceedings of ISMB (1997), pp 258–267
Stam P (1993) Construction of integrated genetic-linkage maps by means of a new computer package—Joinmap. Plant J 3(5):739–744
Van Os H, Stam P, Visser RGF, Van Eck HJ (2005) RECORD: a novel method for ordering loci on a genetic linkage map. Theor Appl Genet 112(1):30–40. doi:10.1007/S00122-005-0097-X
Wu YH, Bhat P, Close TJ, Lonardi S (2008) Efficient and accurate construction of genetic linkage maps from the minimum spanning tree of a graph. PLoS Genet 4(10):e1000212
Wu JX, Jenkins JN, McCarty JC, Lou XY (2011) Comparisons of four approximation algorithms for large-scale linkage map construction. Theor Appl Genet 123(4):649–655. doi:10.1007/S00122-011-1614-8
Acknowledgments
My thanks go to Ian Mackay, Jean-François Rami, Stéphane Dussert and Denis Lespinasse for their kind help and advice.
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Lorieux, M. MapDisto: fast and efficient computation of genetic linkage maps. Mol Breeding 30, 1231–1235 (2012). https://doi.org/10.1007/s11032-012-9706-y
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DOI: https://doi.org/10.1007/s11032-012-9706-y