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Efficient method for the synthesis of novel methyl 4-cinnolinecarboxylate

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Abstract

A new method is designed for the synthesis of some novel methyl 3-aryl/alkyl-4-cinnolinecarboxylate with developed a general Richter cyclization through diazotization strategy of commercially available 2-aryl/alkyl ethynyl aniline and methyl acetate. Most substrates were achieved in moderate to excellent yields in one-pot procedures under mild reaction conditions.

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Acknowledgements

We are grateful for the financial support provided by the University of Jiroft for this research, which leads to our exceptional success.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Jiroft, P. O. Box 8767161167, Jiroft, Iran

    Ali Akbari & Muhammad Saleh Faryabi

  2. Department of Chemistry, Faculty of Science, SGT University, Gurugram, Haryana, 122505, India

    Ravi Tomar

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  1. Ali Akbari
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  2. Muhammad Saleh Faryabi
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  3. Ravi Tomar
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Correspondence to Ali Akbari or Ravi Tomar.

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Akbari, A., Faryabi, M.S. & Tomar, R. Efficient method for the synthesis of novel methyl 4-cinnolinecarboxylate. Mol Divers 27, 1401–1408 (2023). https://doi.org/10.1007/s11030-022-10497-3

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