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Synthesis of polycyclic N-heterocyclic compounds via one-pot three-component cyclization strategy

Molecular Diversity volume 25, pages 2063–2072 (2021)Cite this article

Abstract

Reported herein is an unprecedented and sequential three-component synthetic strategy for the preparation of polycyclic N-heterocyclic compounds. This synthetic protocol enabled the preparation of a series of novel nitrogen-containing pentacyclic compound under convenient conditions in excellent yields and short reaction time. The synthesized products were characterized by IR, 1H NMR, 13C NMR and mass spectra. Furthermore, the definitive structure of target compounds was confirmed by X-ray analysis.

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Affiliations

  1. Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran

    Abdolali Alizadeh, Elham Sanjari & Atefeh Roosta

  2. Department of Inorganic Chemistry, Chemistry and Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran

    Mohammad Reza Halvagar

Authors
  1. Abdolali Alizadeh
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  2. Elham Sanjari
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  3. Atefeh Roosta
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  4. Mohammad Reza Halvagar
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Correspondence to Abdolali Alizadeh.

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Alizadeh, A., Sanjari, E., Roosta, A. et al. Synthesis of polycyclic N-heterocyclic compounds via one-pot three-component cyclization strategy. Mol Divers 25, 2063–2072 (2021). https://doi.org/10.1007/s11030-020-10097-z

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  • DOI: https://doi.org/10.1007/s11030-020-10097-z

Keywords

  • o-Phenylenediamine
  • Aryl isothiocyanate
  • Ninhydrin
  • Polycyclic N-heterocycles