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A new synthesis of \(\varvec{S}\)-aryl uracils from aryl thiols and 6-amino uracils in the presence of NCS

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Abstract

Sulfenylchloride intermediates generated from the reaction of aryl thiols with N-chlorosuccinimide were trapped by 6-amino uracil derivatives to yield 6-amino-5-(arylthio)-pyrimidine-2,4(1H,3H)-dione compounds at room temperature.

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Authors and Affiliations

  1. Chemistry Department, Islamic Azad University, Bushehr Branch, PO Box 7519619555, Bushehr, Iran

    Gholamhossein Khalili

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  1. Gholamhossein Khalili
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Correspondence to Gholamhossein Khalili.

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Khalili, G. A new synthesis of \(\varvec{S}\)-aryl uracils from aryl thiols and 6-amino uracils in the presence of NCS. Mol Divers 20, 963–968 (2016). https://doi.org/10.1007/s11030-016-9685-8

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  • DOI: https://doi.org/10.1007/s11030-016-9685-8

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