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Synthesis of 3-aryl-1,2,4-benzotriazines via intramolecular cyclization of solid-supported o-hydrazidoanilines

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Abstract

An efficient solid-phase protocol for the rapid generation of libraries of biologically promising 1,2,4-benzotriazines, including amino acid-derived components, is described.

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Authors and Affiliations

  1. Grupo de Investigación de Compuestos Heterocíclicos, Departamento de Química, Universidad del Valle, Cali, A.A. 25360, Colombia

    Edwar Cortés, Rodrigo Abonia, Jairo Quiroga & Braulio Insuasty

  2. Instituto de Química Rosario (IQUIR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario-CONICET, Suipacha 531, S2002LRK, Rosario, Argentina

    Luciana Méndez & Ernesto G. Mata

Authors
  1. Edwar Cortés
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  2. Luciana Méndez
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  3. Ernesto G. Mata
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  4. Rodrigo Abonia
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  5. Jairo Quiroga
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  6. Braulio Insuasty
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Correspondence to Ernesto G. Mata.

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Cortés, E., Méndez, L., Mata, E.G. et al. Synthesis of 3-aryl-1,2,4-benzotriazines via intramolecular cyclization of solid-supported o-hydrazidoanilines. Mol Divers 16, 839–846 (2012). https://doi.org/10.1007/s11030-012-9400-3

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