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Toward a practical and waste-free synthesis of thioureas in water

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Abstract

An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and tedious work-up.

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Authors and Affiliations

  1. Research and Technology, Chemistry and Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran

    Najmedin Azizi, Alireza Khajeh-Amiri, Hossein Ghafuri & Mohammad Bolourtchian

Authors
  1. Najmedin Azizi
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  2. Alireza Khajeh-Amiri
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  3. Hossein Ghafuri
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  4. Mohammad Bolourtchian
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Correspondence to Najmedin Azizi.

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Azizi, N., Khajeh-Amiri, A., Ghafuri, H. et al. Toward a practical and waste-free synthesis of thioureas in water. Mol Divers 15, 157–161 (2011). https://doi.org/10.1007/s11030-010-9236-7

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  • DOI: https://doi.org/10.1007/s11030-010-9236-7

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