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Synthesis and structure characterization of new 1,2,4-oxadiazolo[4,5-d]-1,5-benzothiazepines derivatives containing 2-phenyl-1,2,3-triazole through 1,3-dipolar cycloaddition reaction

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Abstract

Reaction of 1,5-benzothiazepines, containing 2-phenyl-1,2,3-triazole 2a–d, with aryl nitrile oxides in CH2 Cl2 at room temperature leads to a series of novel 1,2,4-oxadiazolo[4,5-d]-1,5-benzothiazepine derivatives 3a-l in good yields. The products were characterized by IR, 1H NMR, MS, elemental analyses, X-ray and their spectrum characters were discussed.

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Authors and Affiliations

  1. College of Materials and Chemical Engineering, Hangzhou Normal University, Hangzhou, 310036, China

    De-Bao Yang, Fang-Ming Liu, Chun Yang, Song-Wei Shen, Ying-Lei Zhou & Wei Li

  2. College of Chemistry and Chemical Engineering, Xinjiang University, Wulumuqi, 830046, China

    Fang-Ming Liu, Feng Xu & Jia-Wei Ye

Authors
  1. De-Bao Yang
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  2. Fang-Ming Liu
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  3. Feng Xu
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  4. Chun Yang
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  5. Jia-Wei Ye
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  6. Song-Wei Shen
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  7. Ying-Lei Zhou
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  8. Wei Li
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Correspondence to Fang-Ming Liu.

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Yang, DB., Liu, FM., Xu, F. et al. Synthesis and structure characterization of new 1,2,4-oxadiazolo[4,5-d]-1,5-benzothiazepines derivatives containing 2-phenyl-1,2,3-triazole through 1,3-dipolar cycloaddition reaction. Mol Divers 12, 103–109 (2008). https://doi.org/10.1007/s11030-008-9082-z

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  • DOI: https://doi.org/10.1007/s11030-008-9082-z

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