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A One-Pot Entry to a Novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole Ring System

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Summary

The phosphorus ylide obtained from the reaction between 2-aminobenzo[d]isothiazol-3-one and dimethyl acetylenedicarboxylate in the presence of triphenylphosphine undergoes a smooth intramolecular Wittig-type reaction to produce, in a one-pot reaction, 3-H-benzo[d]pyrazolo[1,5-b]isothiazole-2,3a-dicarboxylic acid dimethyl ester, a novel functionalized heterocyclic compound.

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Authors and Affiliations

  1. Dipartimento Farmaceutico, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43100, Parma, Italy

    Paola Vicini, Matteo Incerti, Rocco Ferretti & Franca Zanardi

Authors
  1. Paola Vicini
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  2. Matteo Incerti
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  3. Rocco Ferretti
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  4. Franca Zanardi
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Correspondence to Paola Vicini.

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Vicini, P., Incerti, M., Ferretti, R. et al. A One-Pot Entry to a Novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole Ring System. Mol Divers 10, 251–253 (2006). https://doi.org/10.1007/s11030-005-9011-3

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  • DOI: https://doi.org/10.1007/s11030-005-9011-3

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