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Transfer hydrogenation using recyclable polymer-supported formate (PSF): Efficient and chemoselective reduction of nitroarenes

Molecular Diversity volume 9, pages 259–262 (2005)Cite this article

Summary

Nitroarenes can be reduced in high yields to the corresponding anilines by transfer hydrogenation using a stable H-donor, polymer-supported formate (PSF) in combination with palladium acetate (catalytic). The reactions occur at 100–120∘C in dimethyl-formamide and the PSF can be recycled for at least three runs. The procedure is chemoselective for nitro group; ester, ketone, aldehyde, and halide substituents on aromatic ring remain unaffected.

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Authors and Affiliations

  1. Department of Chemistry, North Bengal University, Darjeeling, 734 430, India

    Basudeb Basu, Pralay Das & Sajal Das

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  1. Basudeb Basu
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  2. Pralay Das
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  3. Sajal Das
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Correspondence to Basudeb Basu.

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Basu, B., Das, P. & Das, S. Transfer hydrogenation using recyclable polymer-supported formate (PSF): Efficient and chemoselective reduction of nitroarenes. Mol Divers 9, 259–262 (2005). https://doi.org/10.1007/s11030-005-8106-1

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  • DOI: https://doi.org/10.1007/s11030-005-8106-1

Key Words

  • aniline
  • ion-exchange resin
  • nitroarene
  • palladium acetate
  • polymer-supported formate
  • transfer hydrogenation