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Schizophrenia Infrastructures: Local and Global Dynamics of Transformation in Psychiatric Diagnosis-Making in the Twentieth and Twenty-First Centuries

Abstract

This article uses the concept of “diagnosis infrastructures” to propose a framework for narrating the history of schizophrenia as a global category in the twentieth century. Diagnosis infrastructures include the material and architectural arrangements, legal requirements, and professional models that enable both the ways in which patients come to clinics and navigate the world of schizophrenia as well as the means through which clinicians organize their diagnostic work. These infrastructures constitute a framework for how schizophrenia has been identified as a disorder. This article explores three moments in the history of schizophrenia infrastructures in the twentieth century. The first is the German psychiatrist Kurt Schneider’s discussion of first- and second-rank symptoms in the interwar period. The second is the research on criteria for defining schizophrenia within the framework of the WHO International Pilot Study of Schizophrenia at the turn of the 1970s. The third corresponds to the changing infrastructures of mental health care in the context of both global mental health and the changing landscape of schizophrenia research over the last decades.

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Notes

  1. In addition to a review of the literature on the history of schizophrenia, this article is based on several lines of research that I have been following for the last six years on the history and current status of early psychosis. These include archival work on schizophrenia research in France, Germany, and the United States, as well as multisite ethnography of schizophrenia research in France and Germany. In particular, I did 12 months of fieldwork in a university research clinic in France as well as two shorter stays in clinics in German-speaking countries. My participation in this world has also involved attending international conferences as well as interviewing leaders in the field of schizophrenia research internationally. I also participated as a sociologist in collaborative research with a French research team. Some of this research was conducted with Baptiste Moutaud, Marie Reinholdt, and Stefan Reinsch.

  2. On the concept of a transmuted disease see Feudtner (1996).

  3. On infrastructures as solidified practices, see the classic perspective of Hughes (1942).

  4. On this way of framing the problem of psychiatric diagnosis see Noll (2018).

  5. Evidence of this stir may be found in the fallout of the U.S.–U.K. Diagnostic Project which reported that diagnosis of schizophrenia was less stable in New York than in London. Cooper (1972).

  6. Lovell also notes the importance of the IPSS for NIMH research purposes, especially in psychopharmacology.

  7. For instance, in 1957, in a letter to the editor of the American Journal of Psychiatry, psychiatrist Stanley R. Dean proposed that a program of research for schizophrenia be established at the NIMH: “Until now, public support has been directed toward the all-inclusive field of mental health. But psychiatry has long outgrown such swaddling clothes, and the phrase “mental health” now seems too diffuse, too ambiguous, too inadequate to clothe its constituent parts. That is especially true of one of its largest segments—schizophrenia—which many believe may provide the key to all mental disease. It is therefore deserving of much closer public and even professional scrutiny than it has previously received” Dean (1957). Dean (1979) subsequently contributed to fundraising for schizophrenia research and instituted an award for outstanding researchers.

  8. Research Diagnostic Criteria (RDC) were developed at Washington University in St. Louis, Missouri, and led psychiatrists Eli Robbins, Robert Spitzer, Samuel Guze, and clinical psychologist Joan Endicott. The purpose was to delineate precise, consistent criteria for psychiatric diagnoses applicable for research. RDC influenced the development of the DSM-III, which, while not a direct application of RDC, was based on many of its diagnostic descriptions. See Demazeux (2013).

  9. As Robert Cohen, the Director of Clinical Research at NIMH wrote in his 1960 annual report: “The interaction at the regular staff conferences over the eight years of our existence has had a noticeable impact. The individual social or biological scientist no longer approaches a representative problem even in his own discipline without some consideration of its broader implications. Such thinking, by taking into account a wider range of possibilities, leads to a more critical evaluation of the phenomena we are attempting to understand. As the range and depth of our studies show, this atmosphere has not had a stifling effect upon individual initiative; rather, it has promoted careful attention to methodology, precise evaluation of results, and, what is most important, a search for more powerful conceptualizations” National Institute of Mental Health (1960).

  10. https://www.med.unc.edu/pgc, accessed on May 9, 2018. Other figures are mentioned in other publications, however, a variation that might be explained by the fact that participating in the consortium is a relatively informal process. See below.

  11. See http://www.eu-gei.eu/about-the-project, accessed on May 9, 2018.

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Acknowledgements

A very preliminary version of this paper was presented at the European Research Council (ERC)-funded conference, “Historical and Ethnographic Perspectives on the Emergence of Global Mental Health,” organized in Florence, Italy, in June 2017 by Anne M. Lovell, Claudia Lang, and Ursula Read. I thank the organizers for inviting me both to participate in the workshop and to contribute to this special issue, for their comments on subsequent versions of this article, as well as for their patience with my unabashed tendency to stretch deadlines. I also thank two anonymous reviewers for their close reading as well as generous and inspiring comments.

Funding

The research on which this paper is based was funded by the Agence Nationale de la Recherche; the Programme Emergence(s) of the City of Paris; and the Deutsche Forschungsgemeinschaft.

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Henckes, N. Schizophrenia Infrastructures: Local and Global Dynamics of Transformation in Psychiatric Diagnosis-Making in the Twentieth and Twenty-First Centuries. Cult Med Psychiatry 43, 548–573 (2019). https://doi.org/10.1007/s11013-019-09636-7

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Keywords

  • Schizophrenia
  • Infrastructures
  • Psychiatric Diagnosis
  • History of Psychiatry