Abstract
Background: Many have advocated for science and health research in developing world settings. However, there has been less focus on the value of basic and clinical neuroscience research in this context. The current paper focuses on the relevance of a brain-behaviour research initiative in South Africa.
Methods: Workshops sponsored by the University of Cape Town Research Office and by the National Research Foundation have recently focused on the state of South African basic and clinical neuroscience, and on how to strengthen research in these areas. The context of the discussion included national science and health priorities, as well as local research opportunities.
Results: Neuropsychiatric disorders account for the second largest proportion of the burden of disease in South Africa, but receive relatively little research funding. There is a critical need for research, and there are unique research opportunities, in areas such as trauma and resilience, impulsive behaviour (eg violence, sexual risk taking, and substance abuse), and neuroAIDS. Basic, clinical, and systems research can all make important contributions.
Conclusion: There is a need to apprise policy-makers in developing world countries such as South Africa of the need for increased expenditure on basic and clinical neuroscience research. Local and international collaboration may be useful in increasing research capacity in South Africa, and ultimately in improving mental health services.
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Acknowledgements
Many people contributed to the ideas formulated in this document. We wish to acknowledge those who contributed to workshops on a brain-behaviour initiative at the University of Cape Town funded by the UCT Research Office (particularly Rebecca Ackerman and John Tapson), as well as those who participated in a workshop to consider the need for a cross-University brain-behaviour initiative funded by the National Research Foundation of South Africa (including Tiaan Brink, Wayne Christensen, Santy Daya, Lois Harden, Sian Hemmings, Craig Kinnear, Girish Kotwal, Helen Laburn, Dirk Lang, Dee Muller, Pam Naidoo, Jasper Rees, Jane Saunders, Mark Solms, David Spurrett, Ashley van Niekerk, and Joachim Uys). Marilet Sienaert and Therina Theron of UCT’s Research Office gave crucial advice.
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Stein, D.J., Daniels, W., Emsley, R. et al. A brain-behaviour initiative for South Africa: the time is right. Metab Brain Dis 21, 266–271 (2006). https://doi.org/10.1007/s11011-006-9024-3
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DOI: https://doi.org/10.1007/s11011-006-9024-3