Abstract
Background
Evidence indicates that a significant proportion of women drink alcohol during pregnancy. Studies have also suggested that prenatal alcohol consumption was associated with a wide range of adverse outcomes. To the best of our knowledge, this is the first systematic review and meta-analysis aimed to systematically summarize the available evidence on the epidemiology of alcohol consumption among pregnant women in Ethiopia and suggest evidence based recommendations for future clinical practice.
Methods
This systematic review and meta-analysis was followed the PRISMA guidelines. PubMed, SCOPUS and EMBASE databases were searched to identify relevant articles that assessed alcohol consumption among pregnant women in Ethiopia. The Comprehensive Meta-Analysis software version 3.0 was used to conduct a meta-analysis using the random-effect model. Cochran’s Q- and I2-tests were used to assess the heterogeneity of the included studies.
Results
A total of 6361 pregnant women from fifteen primary studies were included in the final analysis. The pooled prevalence estimate of alcohol consumption among pregnant women in Ethiopia was found to be 14.1%. The pooled prevalence of alcohol consumption among pregnant women in Ethiopia was reported to be lower in the studies that used the standardized alcohol consumption assessment tools (9.4%) when compared to the studies that did not use standardized tools (17%). The pooled prevalence of alcohol consumption among pregnant women ranged between 12.8% and 15.5% in leave-one-out sensitivity analysis.
Conclusion
A considerable number of women in Ethiopia consume alcohol during pregnancy. Therefore, early identification and intervention strategies are highly recommended.
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Data Availability
All data generated or analyzed during this study are included in this article.
Abbreviations
- CAGE:
-
Cut-Annoyed-Guilty-Eye opener
- TACE:
-
Tolerance-Annoyed-Cut-down-Eye opener
- AUDIT:
-
Alcohol use disorders identification test
- DSM:
-
Diagnostic and statistical manual of mental disorders
References
Aboye, W., Berhe, T., Birhane, T., & Gerensea, H. (2018). Prevalence and associated factors of low birth weight in Axum town, Tigray, North Ethiopia. BMC Research Notes., 11(1), 684.
Adusi-Poku, Y., Edusei, A. K., Bonney, A. A., Tagbor, H., Nakua, E., & Otupiri, E. (2012). Pregnant women and alcohol use in the Bosomtwe district of the Ashanti region-Ghana. African Journal of Reproductive Health, 16(1), 55–60.
Ahmed, S., Hassen, K., & Wakayo, T. (2018). A health facility-based case-control study on determinants of low birth weight in Dessie town, Northeast Ethiopia: The role of nutritional factors. Nutrition Journal., 17(1), 103.
Anteab, K., Demtsu, B.B., & Megra, M. (2014). Assessment of Prevalence and Associated Factors of Alcohol Use during Pregnancy among the dwellers of Bahir-Dar City Northwest Ethiopia
Asmare, G., Berhan, N., Berhanu, M., & Alebel, A. (2018). Determinants of low birth weight among neonates born in Amhara Regional State Referral Hospitals of Ethiopia: Unmatched case control study. BMC Research Notes., 11(1), 447.
Bitew, M. S., Zewde, M. F., Wubetu, M., & Alemu, A. A. (2020). Consumption of alcohol and binge drinking among pregnant women in Addis Ababa, Ethiopia: Prevalence and determinant factors. PLoS ONE, 15(12), e0243784. https://doi.org/10.1371/journal.pone.0243784
Borenstein, M., Hedges, L. V., Higgins, J., & Rothstein, H. R. (2010). A basic introduction to fixed-effect and random-effects models for meta-analysis. Research Synthesis Methods., 1(2), 97–111.
Centers for Disease Control and Prevention (CDC) (2016) https://www.cdc.gov/ncbddd/fasd/alcohol-use.html
Central Statistical Agency (CSA) [Ethiopia] and ICF. 2016. Ethiopia Demographic and Health Survey 2016. Addis Ababa, Ethiopia, and Rockville, Maryland, USA: CSA and ICF.
Chambers, C. D., Kavteladze, L., Joutchenko, L., Bakhireva, L. N., & Jones, K. L. (2006). Alcohol consumption patterns among women in the Moscow region of Russian Federation. Alcohol, 38, 133–137.
Demelash, H., Motbainor, A., Nigatu, D., Gashaw, K., & Melese, A. (2015). Risk factors for low birth weight in Bale zone hospitals, South-East Ethiopia: A case–control study. BMC Pregnancy and Childbirth., 15(1), 264.
Endeshaw, M., Abebe, F., Bedimo, M., & Asart, A. (2015). Diet and pre-eclampsia: A prospective multicentre case–control study in Ethiopia. Midwifery, 31(6), 617–624.
Ferreira-Borges, C., Esser, M. B., Dias, S., Babor, T., & Parry, C. D. (2015). Alcohol control policies in 46 African countries: Opportunities for improvement. Alcohol and Alcoholism, 50(4), 470–476.
Grum, T., Seifu, A., Abay, M., Angesom, T., & Tsegay, L. (2017). Determinants of pre-eclampsia/Eclampsia among women attending delivery Services in Selected Public Hospitals of Addis Ababa, Ethiopia: A case control study. BMC Pregnancy Childbirth, 17(1), 307.
Hanlon, C., Medhin, G., Alem, A., Tesfaye, F., Lakew, Z., Worku, B., et al. (2009). Impact of antenatal common mental disorders upon perinatal outcomes in Ethiopia: The P-MaMiE population-based cohort study. Tropical Medicine & International Health : TM & IH., 14(2), 156–166.
Health risks and benefits of alcohol consumption. (2000). Alcohol Research & Health, 24(1), 5–11.
Higgins, J. P., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003). Measuring inconsistency in meta-analyses. British Medical Journal., 327(7414), 557.
Isaksen, A. B., Østbye, T., Mmbaga, B. T., & Daltveit, A. K. (2015). Alcohol consumption among pregnant women in Northern Tanzania 2000–2010: A registry-based study. BMC Pregnancy and Childbirth., 15(1), 205.
Landis, J., & Koch, G. (1977). The measurement of observer agreement for categorical data. Biometrics, 33, 1–159.
Mekuriaw, B., Belayneh, Z., Shemelise, T., & Hussen, R. (2019). Alcohol use and associated factors among women attending antenatal care in Southern Ethiopia: A facility based cross sectional study. BMC Research Notes, 12(1), 690.
Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., et al. (2015). Group P-P: preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) statement. Systematic Reviews, 4(1), 1.
Mpelo, M., Kibusi, S. M., Moshi, F., Nyundo, A., Ntwenya, J. E., & Mpondo, B. C. (2018). Prevalence and factors influencing alcohol use in pregnancy among women attending antenatal care in Dodoma region, Tanzania: A cross-sectional study. Journal of Pregnancy, 2018, 8580318.
Ordinioha, B., & Brisibe, S. (2015). Alcohol consumption among pregnant women attending the antenatal clinic of a tertiary hospital in South-South Nigeria. Nigerian Journal of Clinical Practice, 18, 13–17.
Peltzer, K., & Pengpid, S. (2019). Maternal alcohol use during pregnancy in a general national population in South Africa. The South African Journal of Psychiatry: SAJP: THe Journal of the Society of Psychiatrists of South Africa, 25, 1236. https://doi.org/10.4102/sajpsychiatry.v25i0.1236
Popova, S., Lange, S., Probst, C., Shield, K., Kraicer-Melamed, H., Ferreira-Borges, C., & Rehm, J. (2016). Actual and predicted prevalence of alcohol consumption during pregnancy in the WHO African Region. Tropical Medicine & International Health, 21(10), 1209–1239.
Rehm, J., Mathers, C., Popova, S., Thavorncharoensap, M., Teerawattananon, Y., & Patra, J. (2009). Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet, 373(9682), 2223–2233.
Robertson, E., Celasun, N., & Stewart, D. (2003). Risk factors for postpartum depression. World Health Organization.
Sanou, A. S., Diallo, A. H., Holding, P., Nankabirwa, V., Engebretsen, I., Ndeezi, G., & Kashala-Abotnes, E. (2017). Maternal alcohol consumption during pregnancy and child’s cognitive performance at 6–8 years of age in rural Burkina Faso: An observational study. PeerJ, 5, e3507. https://doi.org/10.7717/peerj.3507
Stang, A. (2010). Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. European Journal of Epidemiology, 25(9), 603–605.
Tafere, G. (2015). A review on traditional fermented beverages of Ethiopian. Journal Natural Science Resources, 5, 94–102.
Tesfaye, G., Demlew, D., G/tsadik, M., Habte, F., Molla, G., Kifle, Y., et al. (2020). The prevalence and associated factors of alcohol use among pregnant women, 2019 attending antenatal care at public hospitals Addis Ababa, Ethiopia. BMC Psychiatry, 20, 337. https://doi.org/10.1186/s12888-020-02747-1
Tessema, G. A., Tekeste, A., & Ayele, T. A. (2015). Preeclampsia and associated factors among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia: A hospital-based study. BMC Pregnancy Childbirth, 15(1), 73.
Tesso, F. Y., Woldesemayat, L. A., & Kebede, D. B. (2017). Magnitude of substance use and associated factors among pregnant women attending Jimma town public health facilities, Jimma Zone, Oromia regional state Southwest Ethiopia. Clinics Mother Child Health, 14, 275.
Taye, M., Afework, M., Fantaye, W., Diro, E., & Worku, A. (2018). Factors associated with congenital anomalies in Addis Ababa and the Amhara region, Ethiopia: A case-control study. BMC Pediatr, 18(1), 142.
Viljoen, D. L., Carr, L. G., Foroud, T. M., Brooke, L., & Ramsay, M. L. (2001). Alcohol dehydrogenase-2*2 allele is associated with decreased prevalence of fetal alcohol syndrome in the mixed-ancestry population of the Western Cape Province. South Africa, 25, 1719–1722.
WHO guidelines for the identification and management of substance use and substance use disorders in pregnancy. WHO Library Cataloguing-in Publication Data. 2014
World Health Organization (WHO). Global Information System on Alcohol and Health (GISAH). WHO: Geneva, Switzerland, 2014. Available from: http://apps.who.int/gho/
Wubetu, A. D., Habte, S., & Dagne, K. (2019). Prevalence of risky alcohol use behavior and associated factors in pregnant antenatal care attendees in Debre Berhan, Ethiopia, 2018. BMC Psychiatry, 19(1), 250. https://doi.org/10.1186/s12888-019-2225-1
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The author (BD) conceptualized the study, performed the search and quality assessment, conducted the analyses, developed, and drafted the manuscript, and approved the final manuscript. SW, DW, TT, GA and AB performed the search, data extraction, quality assessment and approved the final manuscript. All authors reviewed and approved the final manuscript.
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Duko, B., Bedaso, A., Wolka, S. et al. The Prevalence of Alcohol Consumption Among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis. Matern Child Health J 26, 1800–1810 (2022). https://doi.org/10.1007/s10995-021-03286-1
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DOI: https://doi.org/10.1007/s10995-021-03286-1