Abstract
Purpose
Opioid use disorder among women of childbearing age has reached epidemic proportions. In rural regions of the United States, recruiting perinatal women who use nonmedical opioids to participate in research is wrought with challenges, including barriers such as community stigma, lack of transportation, and time constraints. The current study describes our process and challenges of recruiting pregnant and postpartum women in rural Indiana consisting of women who misuse opioids and those who do not.
Description
We employed multiple strategies to recruit participants. Methods included (1) sampling from healthcare facilities based on referrals from front-desk staff and frontline healthcare workers; (2) dissemination of flyers and brochures within healthcare facilities and the community, supported with onsite research assistant presence; (3) digital methods coupled with snowball sampling; and (4) local community talks that provided information about the study.
Assessment
Our multiple recruitment efforts revealed that building relationships with community stakeholders was key in recruiting women who use nonmedical opioids, but that digital methods were more effective in recruiting a larger sample of pregnant and postpartum women in a short amount of time.
Conclusion
We conclude by making several recommendations to enhance academic-community partnerships in order to bolster sample sizes for prolonged research studies. Furthermore, we highlight the need to destigmatize addiction in order to better serve hard-to-reach populations through research and practice.
Notes
Prior to each stage of the modifications outlined below, the first author submitted an amendment form to IRB. Data collection did not commence until their approval was granted.
References
Admon, L. K., Haefner, J. K., Kolenic, G. E., Chang, T., Davis, M. M., & Moniz, M. H. (2016). Recruiting pregnant patients for survey research: A head to head comparison of social media-based versus clinic-based approaches. Journal of Medical Internet Research, 18(12), e326. https://doi.org/10.2196/jmir.6593
Bassett-Gunter, R. L., Levy-Milne, R., Naylor, P. J., Symons Downs, D., Benoit, C., Warburton, D. E. R., & Rhodes, R. E. (2013). Oh baby! Motivation for healthy eating during parenthood transitions: A longitudinal examination with a theory of planned behavior perspective. International Journal of Behavioral Nutrition and Physical Activity, 10(1), 88. https://doi.org/10.1186/1479-5868-10-88
Bonevski, B., Randell, M., Paul, C., Chapman, K., Twyman, L., Bryant, J., & Hughes, C. (2014). Reaching the hard-to-reach: A systematic review of strategies for improving health and medical research with socially disadvantaged groups. BMC Medical Research Methodology, 14(1), 42. https://doi.org/10.1186/1471-2288-14-42
Desai, N., Kraus, S. W., & Houchins, J. R. (2017). Factors to consider for reducing us opioid-related deaths: Looking beyond access. JAMA Psychiatry, 74(11), 1171–1171. https://doi.org/10.1001/jamapsychiatry.2017.2586
Frew, P. M., Saint-Victor, D. S., Isaacs, M. B., Kim, S., Swamy, G. K., Sheffield, J. S., & Ault, K. (2014). Recruitment and retention of pregnant women into clinical research trials: An overview of challenges, facilitators, and best practices. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 59(Suppl 7), S400–S407. https://doi.org/10.1093/cid/ciu726
Howard, J., & Beckwith, L. (1996). Issues in subject recruitment and retention with pregnant and parenting substance-abusing women. NIDA Research Monograph, 166, 68–86
Kelly, J. F., & Westerhoff, C. M. (2010). Does it matter how we refer to individuals with substance-related conditions? A randomized study of two commonly used terms. International Journal of Drug Policy, 21(3), 202–207
Krans, E. E., & Patrick, S. W. (2016). Opioid use disorder in pregnancy: Health policy and practice in the midst of an epidemic. Obstetrics and Gynecology, 128(1), 4–10. https://doi.org/10.1097/AOG.0000000000001446
McLeroy, K. R., Bibeau, D., Steckler, A., & Glanz, K. (1988). An ecological perspective on health promotion programs. Health Education Quarterly, 15(4), 351–377
Nasser, N., Grady, D., & Balke, C. W. (2011). Commentary: Improving participant recruitment in clinical and translational research. Academic Medicine: Journal of the Association of American Medical Colleges, 86(11), 1334–1335. https://doi.org/10.1097/ACM.0b013e3182302831
Olander, E. K., Smith, D. M., & Darwin, Z. (2018). Health behaviour and pregnancy: A time for change. Journal of Reproductive and Infant Psychology, 36(1), 1–3. https://doi.org/10.1080/02646838.2018.1408965
Placek, C. D., Srinivas, V., Jayakrishna, P., & Madhivanan, P. (2019). Mixed-methods and repeated measures in substance use research: Implications for informant accuracy. Field Methods, 31(4), 344–358
Promislow, J. H. E., Makarushka, C. M., Gorman, J. R., Howards, P. P., Savitz, D. A., & Hartmann, K. E. (2004). Recruitment for a community-based study of early pregnancy: The right from the start study. Paediatric and Perinatal Epidemiology, 18(2), 143–152. https://doi.org/10.1111/j.1365-3016.2003.00546.x
Shaghaghi, A., Bhopal, R. S., & Sheikh, A. (2011). Approaches to recruiting “Hard-To-Reach” populations into research: A review of the literature. Health Promotion Perspectives, 1(2), 86–94. https://doi.org/10.5681/hpp.2011.009
Stokols, D. (1996). Translating social ecological theory into guidelines for community health promotion. American Journal of Health Promotion, 10(4), 282–298
Sui, Z., Turnbull, D., & Dodd, J. (2013). Enablers of and barriers to making healthy change during pregnancy in overweight and obese women. The Australasian Medical Journal, 6(11), 565–577. https://doi.org/10.4066/AMJ.2013.1881
Thompson, E. L., Vamos, C. A., & Daley, E. M. (2017). Physical activity during pregnancy and the role of theory in promoting positive behavior change: A systematic review. Journal of Sport and Health Science, 6(2), 198–206. https://doi.org/10.1016/j.jshs.2015.08.001
van der Zande, I. S., van der Graaf, R., Hooft, L., & van Delden, J. J. (2018). Facilitators and barriers to pregnant women’s participation in research: A systematic review. Women and Birth, 31(5), 350–361
Acknowledgements
The authors would like to thank the partner institutions and study participants for dedicating their time to this study. This project was supported, in part, with support from the Indiana Clinical and Translational Sciences Institute funded, in part by Award Number UL1TR002529 from the National Institutes of Health, National Center for Advancing Translational Sciences, Clinical and Translational Sciences Award. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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Placek, C.D., Place, J.M. & Wies, J. Reflections and Challenges of Pregnant and Postpartum Participant Recruitment in the Context of the Opioid Epidemic. Matern Child Health J 25, 1031–1035 (2021). https://doi.org/10.1007/s10995-021-03143-1
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DOI: https://doi.org/10.1007/s10995-021-03143-1