The study was aimed at investigating the biologically active compounds in Pleurotus sajor-caju wild edible mushroom and its potential antioxidant and antibacterial activity against multidrug-resistant (MDR) Salmonella typhi (Accession No. KT037135). Gas chromatography-mass spectrometry (GC–MS) and Fourier transform infrared spectroscopy (FT-IR) analysis exposed the presence of bioactive components. The antioxidant properties were evaluated using the free radical scavenging method 1,1-diphenyl-2-picrylhydrazyl (DPPH). The methanolic extract of the P. sajor-caju was exhibited 67.42 ± 0.25% of antioxidant activity according to the DPPH. The bactericidal activity was evaluated and the results showed that the S. typhi growth was considerably decreased in a dose-dependent approach. Thus, it is recommended that the methanolic extract of the P. sajor-caju could be a lead drug and chosen to very good antioxidant activity and also effectively control the MDR S. typhi.
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This work is supported by the Department of Biotechnology, Mahendra Arts and Science College (Autonomous), Namakkal, Tamil Nadu, India, and the Department of Science and Technology, Government of India, India (DST-FIST sponsored—Ref. No. SR/FST/College-232/2014). The author Ashraf Y Z Khalifa acknowledge the Deanship of Scientific Research at King Faisal University, for the financial support under Nasher track (Grant No. 186140).
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Kandasamy, S., Chinnappan, S., Thangaswamy, S. et al. Assessment of Antioxidant, Antibacterial Activities and Bioactive Compounds of the Wild Edible Mushroom Pleurotus sajor-caju. Int J Pept Res Ther 26, 1575–1581 (2020). https://doi.org/10.1007/s10989-019-09969-2