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Usually overlooked problems related with measurements of high-heat effects using power compensation isothermal titration calorimetry

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Abstract

This research paper deals with the problems associated with power compensation isothermal titration calorimetry. It is demonstrated that at processes, accompanied by large heat effects or/and slow kinetic processes, it is possible to obtain different values of enthalpies with different instruments and different setting parameters. Dynamic power compensation mode in modern calorimeters could namely lead to overcompensation of the heat effects, giving results which are strongly dependent on the chosen experimental parameters. In order to avoid these problems with modern instruments, first the check of a raw signal is proposed and in the case where the switching effect is observed, the experiments have to be carried out with low or disabled power compensation. In this way, the duration of experiments will be longer and the measuring range will be narrower, but the experimental results will be correct.

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Acknowledgements

Ž.M. is grateful to Slovenian Research Agency for the position of young researcher, enabling him the doctoral study. I.Č. would like to acknowledge the grant of The Public Scholarship, Development, Disability and Maintenance Fund of the Republic of Slovenia enabling her research work and doctoral studies at the University of Ljubljana. The work was supported by the Slovenian Research Agency through Grant No. P1-0201.

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  1. Faculty of Chemistry and Chemical Technology, Večna pot 113, University of Ljubljana, 1000, Ljubljana, Slovenia

    Žiga Medoš, Isidora Čobanov, Marija Bešter-Rogač & Bojan Šarac

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  1. Žiga Medoš
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  2. Isidora Čobanov
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  3. Marija Bešter-Rogač
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Correspondence to Bojan Šarac.

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Medoš, Ž., Čobanov, I., Bešter-Rogač, M. et al. Usually overlooked problems related with measurements of high-heat effects using power compensation isothermal titration calorimetry. J Therm Anal Calorim 145, 87–96 (2021). https://doi.org/10.1007/s10973-020-09663-2

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