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Melt reaction and structural analysis based on poly(butylene terephthalate) and oligo(lactic acid) with addition of butanediol

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Abstract

The poly(1,4-butylene terephthalate-co-DL-lactide) (BLA) copolymers were successfully prepared by the melt reaction between poly(1,4-butylene terephthalate) (PBT) and DL-oligo(lactic acid) (OLA) in the presence of 1,4-butanediol (BDO) without any catalysts. The transesterification between butylenes terephthalate (BT), 1,4-butanediol and lactide (LA) segments during the reaction was confirmed by the 1H NMR analysis. The chemical structure of the copolymers was further investigated by the 13C NMR and two-dimensional 1H–13C HMQC (heteronuclear multiple quantum correlation) technique. The effect of reaction temperatures and the starting feed ratios on the molecular microstructures, molecular weights, solubility and thermal stability of the copolyesters was extensively studied. The sequence length of BT (NBT) was found to play a vital role on the solubility and thermal behaviors of the resulting copolyesters. The copolyesters with NBT in the range of 2.8 and 7.3 were soluble in chloroform. The B10LA40 copolyester with the shortest NBT of 2.8 exhibited almost the lowest glass-transition temperature (Tg), crystallization temperature (Tc), melting temperature (Tm), crystallization enthalpy (ΔHc) and melting enthalpy (ΔHm) as compared with the other copolyesters. The copolyester of B10LA40 was able to hydrolytically degrade and the fabricated scaffold that showed good biocompatibility towards the human bone marrow stromal cells.

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Acknowledgments

Financial support for this work was provided by the Program for New Century Excellent Talents in University (NCET-06-0574), the Program for Innovative Research Team of Nanchang University, Program for Innovative Research Team in University of Jiangxi Province, and Program for Changjiang Scholars and Innovative Research Team in University (IRT0730).

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Authors and Affiliations

  1. Department of Chemistry, School of Science, Nanchang University, Xuefu Road 999, Nanchang, 330031, People’s Republic of China

    Licheng Tan & Yiwang Chen

  2. Institute of Polymers/Institute for Advanced Study, Nanchang University, Xuefu Road 999, Nanchang, 330031, People’s Republic of China

    Yiwang Chen, Weihua Zhou & Xiaohui He

  3. The First Affiliated Hospital of Nanchang University, Yongwaizheng Road 17, Nanchang, 330006, People’s Republic of China

    Yang Wang

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  1. Licheng Tan
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  2. Yiwang Chen
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  4. Weihua Zhou
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  5. Xiaohui He
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Correspondence to Yiwang Chen or Weihua Zhou.

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Tan, L., Chen, Y., Wang, Y. et al. Melt reaction and structural analysis based on poly(butylene terephthalate) and oligo(lactic acid) with addition of butanediol. J Therm Anal Calorim 99, 269–275 (2010). https://doi.org/10.1007/s10973-009-0101-9

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  • DOI: https://doi.org/10.1007/s10973-009-0101-9

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