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Thermokinetic analysis of the hydration process of calcium phosphate cement

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Abstract

A microcalorimeter (Setaram c-80) was used to study the thermokinetics of the hydration process of calcium phosphate cement (CPC), a biocompatible biomaterial used in bone repair. The hydration enthalpy was determined to be 35.8 J g–1 at 37.0°C when up to 80 mg CPC was dissolved in 2 mL of citric buffer. In the present study, parameters related to time constants of the calorimeter were obtained by fitting the recorded thermal curves with the function θ=Ae–?t(1– e–?2t). The real thermogenetic curves were then retrieved with Tian function and the transformation rate of the hydration process of CPC was found to follow the equation α=1–[1–(0.0075t)3]3. The microstructures of the hydrated CPC were examined by scanning electron microscopy. The nano-scale flake microstructures are due to crystallization of calcium phosphate and they could contribute to the good biocompatibility and high bioactivity.

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Authors and Affiliations

  1. Key Lab of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, P. R. China, 100084

    W.Y. Gao, Y.W. Wang & Z.W. Yu1

  2. The Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing, P. R. China, 100084

    L.M. Dong

Authors
  1. W.Y. Gao
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  2. Y.W. Wang
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  3. L.M. Dong
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  4. Z.W. Yu1
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Correspondence to Z.W. Yu1.

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Gao, W., Wang, Y., Dong, L. et al. Thermokinetic analysis of the hydration process of calcium phosphate cement. J Therm Anal Calorim 85, 785–789 (2006). https://doi.org/10.1007/s10973-005-7433-x

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  • DOI: https://doi.org/10.1007/s10973-005-7433-x

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