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225Ac production via 226Ra (μ−, n ν) 225Fr reaction with 226Ra target

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Abstract

Actinium-225 (225Ac) has attracted global attention due to its applications in cancer therapy. A new 225Ac production method is proposed by muon nuclear-capture reactions with negative muons (μ−) irradiating on a 226Ra target. The 225Fr is produced by 226Ra (μ−, n ν) 225Fr reaction and decays to 225Ra. The 225Ra subsequently decays to 225Ac. The method produces no carrier-added 225Ac, and 213Bi from a 225Ac-213Bi generator. The production method by muon nuclear-capture reactions with the 226Ra target is described. The radioactivity of 225Ac and 213Bi are calculated assuming the reaction branching ratio of 226Ra (μ−, n ν) 225Fr.

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Acknowledgements

A part of the research was funded by the ImPACT Program of the Council for Science, Technology, and Innovation (Cabinet Office, Government of Japan) [43].

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  1. RIKEN Nishina Center for Accelerator-Based Science, 2–1 Hirosawa, Wako, Saitama, 351–0106, Japan

    Teiichiro Matsuzaki & Hiroyoshi Sakurai

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Correspondence to Teiichiro Matsuzaki.

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Matsuzaki, T., Sakurai, H. 225Ac production via 226Ra (μ−, n ν) 225Fr reaction with 226Ra target. J Radioanal Nucl Chem (2024). https://doi.org/10.1007/s10967-024-09514-6

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