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Evaluation of dose enhancement effect of bismuth oxide nanoparticles by means of MAGAT and nPAG gel dosimeters

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Abstract

Dose enhancement factor (DEF) in the presence of heavy nanoparticles in tumors can be evaluated by irradiation of gel dosimeters impregnated with nanoparticles (NPs); however, an important issue is whether all gel dosimeters are suitable to evaluate this factor. In this study, we evaluated MAGAT and nPAG for measuring DEF of bismuth oxide nanoparticles. Results revealed that DEF decreased for gels combined with nanoparticles compared to pure gel (without nanoparticles). Hence, it can be concluded that the characteristics of nanoparticles and the components of the gel can significantly influence the possibility of using a gel dosimeter to evaluate DEF.

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Funding

The research leading to these results received funding from Tehran University of Medical Sciences under Grant Agreement No 96–03-30–36303.

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Authors and Affiliations

  1. Department of Medical Physics and Medical Engineering, School of Medicine, Tehran University of Medical Sciences, 1417613151, Tehran, Iran

    Zahra Alyani Nezhad, Ghazale Geraily & Elham Hossein Nezhad

  2. Radiation Oncology Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran

    Ghazale Geraily

  3. Department of Medical Physics, Faculty of Paramedical Sciences, Ilam University of Medical Sciences, Ilam, Iran

    Wrya Parwaie

Authors
  1. Zahra Alyani Nezhad
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  2. Ghazale Geraily
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  3. Wrya Parwaie
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  4. Elham Hossein Nezhad
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Correspondence to Ghazale Geraily.

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Alyani Nezhad, Z., Geraily, G., Parwaie, W. et al. Evaluation of dose enhancement effect of bismuth oxide nanoparticles by means of MAGAT and nPAG gel dosimeters. J Radioanal Nucl Chem 331, 1683–1689 (2022). https://doi.org/10.1007/s10967-022-08242-z

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  • DOI: https://doi.org/10.1007/s10967-022-08242-z

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