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A normoxic acrylic acid polymer gel for dosimetery in radiation therapy

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Abstract

A novel low toxic normoxic polymer gel dosimeter containing acrylic acid monomer is prepared and characterized for dosimetry in radiotherapy. Gel samples were fabricated under normal atmospheric conditions. The gels were irradiated to different doses using a medical linear accelerator at 6 MV X-ray energy to investigate the dose response and other characteristics. The dose response was evaluated in terms of relaxation rate using NMR relaxometry, which was carried out using a 0.5 T NMR technique. The sample temperature during the NMR relaxometry was fixed at 20.0 ± 0.1 °C using a thermostatic circulating water bath connected to the NMR relaxometry. A significant improvement in the performance of the dosimeter was noticed for acrylic acid gel with the addition of MgCl2 salt. The sensitivity of gel with 0.6 M MgCl2 was about 4.6 times of the same gel without MgCl2. The total uncertainty of the R2 measurements was about 5%. Different important parameters such as dose rate, beam quality, NMR scanning temperature, and stability of the dose response were investigated in this study.

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Acknowledgements

The authors would like to acknowledge the support of Hashemite University (HU 52-5-2014) in funding this project.

Funding

Funding was provided by the hashemite university, (Grant HU 52–5-2014),

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Authors and Affiliations

  1. Medical Imaging Department, Faculty of Applied Medical Sciences, The Hashemite University, P. O. box 330127, Zarqa, 13133, Jordan

    Khalid A. Rabaeh & Ammar A. Oglat

  2. School of Basic Sciences and Humanities, German Jordanian University, Amman, 11180, Jordan

    Issra’ M. E. Hammoudeh

  3. Biomedical Physics Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    Belal Moftah

  4. Physics Department, Faculty of Science, Yarmouk University, Irbid, 21163, Jordan

    Molham M. Eyadeh

  5. Physics Department, Faculty of Science, The Hashemite University, P. O. Box 330127, Zarqa, 13133, Jordan

    Feras M. Aldweri

  6. Chemistry Department, Faculty of Science, The Hashemite University, P. O. Box 330127, Zarqa, 13133, Jordan

    Ala’ J. Abdel-Qader

  7. Medical Physics Unit, McGill University, Montréal, Canada

    Belal Moftah & Slobodan Devic

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  1. Khalid A. Rabaeh
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Correspondence to Khalid A. Rabaeh.

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Rabaeh, K.A., Hammoudeh, I.M.E., Moftah, B. et al. A normoxic acrylic acid polymer gel for dosimetery in radiation therapy. J Radioanal Nucl Chem 331, 665–672 (2022). https://doi.org/10.1007/s10967-021-08143-7

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