Historical and radiopharmaceutical relevance of [18F]FDG

A Commentary to this article is available


The 2-[18F]fluoro-2-deoxy-d-glucose ([18F]FDG) is the most well-known radiopharmaceutical positron emitter, in both clinical and preclinical fields. Based on a literature review of research from the last 40 years, this paper focuses on the most important aspects of [18F]FDG production and its evolution over time. Possible future perspectives of this important radiotracer are also discussed.

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Petroni, D., Menichetti, L. & Poli, M. Historical and radiopharmaceutical relevance of [18F]FDG. J Radioanal Nucl Chem 323, 1017–1031 (2020). https://doi.org/10.1007/s10967-020-07013-y

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  • [18F]FDG
  • PET
  • Automated synthesizer
  • Quality control
  • Legislation