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The study of Zr adsorption on nanodispersed hydroxyapatite: X-ray photoelectron study

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Abstract

Elemental and phase composition of hydroxyapatite (HA) nanoparticle surface with absorbed zirconium were studied with X-ray photoelectron spectroscopy. Zr4+ adsorption on HA nanocrystals as a function of hydrochloric solution pH was established. The mechanism of interaction of zirconium with the HA surface was discussed. The obtained results are fundamental for 89Zr-based radiopharmaceuticals with a new design.

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Acknowledgements

The authors acknowledge support from Lomonosov Moscow State University Program of Development for providing access to the XPS facility. The work was partially supported by the RFBR Grants 18-33-00649 and 17-03-00277a.

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Authors and Affiliations

  1. Department of Nuclear and Radiation Medicine, National Research Center, Kurchatov Institute, Akademika Kurchatova pl., 1, Moscow, Russia, 123098

    Yuri A. Teterin, Andrey G. Kazakov, Anton Yu Teterin, Stanislav V. Dvorak, Konstantin I. Maslakov & Kirill E. Ivanov

  2. Chemistry Department, Lomonosov Moscow State University, Leninskie Gory, 1, Moscow, Russia, 119991

    Yuri A. Teterin, Andrey G. Kazakov & Alexander V. Severin

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  1. Yuri A. Teterin
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Teterin, Y.A., Kazakov, A.G., Teterin, A.Y. et al. The study of Zr adsorption on nanodispersed hydroxyapatite: X-ray photoelectron study. J Radioanal Nucl Chem 321, 341–347 (2019). https://doi.org/10.1007/s10967-019-06586-7

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