Development and optimization of an on-site sequential extraction system for radiobioassay in radiation emergency
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An on-site sample preparation system (OS) was developed and tested for fast measurement of alpha- and beta-emitting radionuclides in radiation emergencies. Sequential analysis of 238,239Pu, 241Am and 90Sr was performed using OS for in vitro bioassay. The chemical recovery yields at different flow rates were determined to establish the optimal preparation condition. Multiple separations of target radionuclides in synthetic urine samples were performed and the results were reviewed. The overall chemical recoveries were reasonably consistent. The turnaround time from sample preparation to counting was reduced compared to traditional methods by up to 61 %.
KeywordsOn-site radiobioassay Sequential extraction system Radiobioassay Radiation emergency
This study was supported by a Grant of the Korea Institute of Radiological and Medical Sciences (KIRAMS), funded by Ministry of Science, ICT and Future Planning, Republic of Korea (1711031808/50581-2016).
- 1.International Atomic Energy Agency (2005) Generic procedures for medical response during a nuclear or radiological emergency. Vienna, AustriaGoogle Scholar
- 7.L’Annunziata MF (ed) (2012) Handbook of radioactivity analysis, 3rd edn. Academic Press, San DiegoGoogle Scholar
- 8.Eichrom Technologies I (2006) Analytical procedures-americium, neptunium, plutonium, thorium, curium, uranium, and strontium in water (with vacuum box system). Eichrom Technologies, IncGoogle Scholar
- 10.ANSI (2011) Performance criteria for radiobioassay, Standard N13.30. American National Standards InstituteGoogle Scholar
- 12.Horwitz EP (1998) Extraction chromatography of actinides and selected fission products: principles and achievement of selectivity. International workshop on the application of extraction chromatography in radionuclide measurement. IRMM, Geel, pp 9–10Google Scholar
- 14.Li C, Battisti P, Berard P, Cazoulat A, Cuellar A, Cruz-Suarez R, Dai X, Giardina I, Hammond D, Hernandez C, Kiser S, Ko R, Kramer-Tremblay S, Lecompte Y, Navarro E, Navas C, Sadi B, Sierra I, Verrezen F, Lopez MA (2015) EURADOS intercomparison on emergency radiobioassay. Radiat Prot Dosim 167:472–484CrossRefGoogle Scholar
- 15.National Council on Radiation Protection and Measurements (2009) Management of persons contaminated with radionuclides handbook, NCRP report no 161. National Council on Radiation Protection and Measurements, Bethesda, MD, p 1. https://app.knovel.com/. Accessed 5 May 2016 (xiii, 276 p.)