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Study of hydrophilic materials as tissue equivalent phantoms for positron emission tomography

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Abstract

Positron emission tomography is a nuclear medicine procedure allowing biochemical processes to be investigated by in vivo imaging. Tissue equivalent materials have generated great interest in the diagnosis and treatment of cancer. This study describes the preparation of phantoms and methods employed to determine oxygen levels in cross-linked hydrophilic co-polymers with a view to extend this further for samples at low concentrations of oxygen. The physicochemical characteristics of hydroxyethyl methacrylate and methyl methacrylate/vinyl pyrrolidone were studied by measuring the hydration rate in biological fluids.

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Acknowledgments

The author extends his appreciation to the Deanship of Scientific Research at King Saud University for funding this work through Research Project number NFG2-07-33. The author would like to thank Prof. NM Spyrou and Dr. DJ Highgate for useful discussions throughout.

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Authors and Affiliations

  1. Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh, 11433, Saudi Arabia

    M. A. Alkhorayef

  2. Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford, Surrey, GU2 7XH, UK

    M. A. Alkhorayef

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  1. M. A. Alkhorayef
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Correspondence to M. A. Alkhorayef.

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Alkhorayef, M.A. Study of hydrophilic materials as tissue equivalent phantoms for positron emission tomography. J Radioanal Nucl Chem 306, 745–749 (2015). https://doi.org/10.1007/s10967-015-4385-x

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  • DOI: https://doi.org/10.1007/s10967-015-4385-x

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