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Preparation and deployment of indigenous 125I-seeds for the treatment of prostate cancer: Dawn of prostate brachytherapy in India

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Abstract

‘Permanent seed implantation’ using 125I- seeds has emerged as an effective treatment modality for management of prostate cancer. An indigenous technology for the production of 125I brachytherapy sources (‘BARC 125I Ocu-Prosta seed’) has been developed. In this current work, we describe an overview of our experience on large scale production of 125I brachytherapy sources, their quality assessment, in vivo bio-evaluation and initial experience on their journey from bench to bed-side for the treatment of prostate cancer.

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Authors and Affiliations

  1. Isotope Production & Applications Division, Bhabha Atomic Research Centre, Mumbai, 400 085, India

    Sanjay Kumar Saxena, Archana Mukherjee, Yogendra Kumar, Ramu Ram, A. S. Tapase & Ashutosh Dash

  2. P.D. Hinduja National Hospital & Medical Research Centre, Mahim, Mumbai, 400016, India

    Vivek J. Anand

Authors
  1. Sanjay Kumar Saxena
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  2. Archana Mukherjee
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  3. Yogendra Kumar
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  4. Ramu Ram
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  5. A. S. Tapase
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  6. Vivek J. Anand
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  7. Ashutosh Dash
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Correspondence to Ashutosh Dash.

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Saxena, S.K., Mukherjee, A., Kumar, Y. et al. Preparation and deployment of indigenous 125I-seeds for the treatment of prostate cancer: Dawn of prostate brachytherapy in India. J Radioanal Nucl Chem 302, 1237–1243 (2014). https://doi.org/10.1007/s10967-014-3521-3

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  • DOI: https://doi.org/10.1007/s10967-014-3521-3

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