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Separation of 90Y from 90Sr using sequential multiple column extraction chromatography

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Abstract

The distribution coefficient measurements on Y(III) and Sr(II) were performed using ditertiarybutyl dicyclohexano 18-crown-6 (Sr-selective resin) and N,N,N′,N′-tetraoctyldiglycolamide (Y-selective resin) in HNO3, HCl and HClO4 media. Separation factors (90Y/90Sr) based on distribution coefficient data suggested that perchloric acid is distinctly better medium as compared to nitric acid/hydrochloric acid. The mechanism of extraction changes with the nature and concentration of acid and is responsible for the high selectivity in perchloric acid medium. Sequential column studies were carried out on tracers (radioactive/stable) employing Sr-selective/Y-selective extraction chromatographic resins as stationary phases. The final elution of 90Y was done in 0.01 M EDTA at pH 4.0 which can be used for clinical applications after radiochemical processing.

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References

  1. Pfenning G, Klewe-Nebenius H, Seelmann-Eggebert W (1995) Karlsruher Nuklidkarte, 6th edn. Forschungszentrum Karlsruhe, Karlsruhe

    Google Scholar 

  2. Vanura P, Makrlík E (2002) J Radioanal Nucl Chem 251(3):499–501

    Article  CAS  Google Scholar 

  3. Goldenberg DM (2001) Crit Rev Oncol Hemat 39:195–201

    Article  CAS  Google Scholar 

  4. Davies AJ (2007) Oncogene 26:3614–3628

    Article  CAS  Google Scholar 

  5. Kwekkeboom DJ, Mueller-Brand J, Paganelli G, Anthony LB, Pauwel S, Kvols LK, O’Dorisio TM, Valkema R, Bodei L, Chinol M, Maecke HR, Krenning EP (2005) J Nucl Med 46(Suppl. 1):62S–66S

    CAS  Google Scholar 

  6. Chakravarty R, Dash A, Pillai MRA (2012) Cancer Biother Radio 27:621–641

    CAS  Google Scholar 

  7. Nichols AL, Aldama DL, Verpelli M (2008) Handbook of Nuclear Data for Safeguards: Database extensions. International Nuclear Data Committee, Vienna

    Google Scholar 

  8. Yttriga: EPAR Scientific Discussion, European Medicines Agency, 29.10.2006

  9. Chinol M, Hnatowich DJ (1987) J Nucl Med 28:1465–1470

    CAS  Google Scholar 

  10. Horwitz EP, McAlister DR (2006) Sep Sci Technol 41:2163–2182

    Article  CAS  Google Scholar 

  11. Dietz LM, Horwitz EP (1992) Appl Radiat Isot 43:1093–1101

    Article  CAS  Google Scholar 

  12. Hsieh BT, Ting G, Hsieh HT, Shen LH (1993) Appl Radiat Isot 44:1473–1480

    Article  CAS  Google Scholar 

  13. Achuthan PV, Dhami PS, Kannan R, Gopalakrishnan V, Ramanujam A (2000) Sep Sci Technol 35:261–270

    Article  CAS  Google Scholar 

  14. Dhami PS, Naik PW, Pandey U, Dudwadkar NL, Kannan R, Achuthan PV, Moorthy AD, Jambunathan U, Munshi SK, Dey PK, Pandey U, Venkatesh M (2007) Sep Sci Technol 41:1107–1121

    Article  Google Scholar 

  15. Xu Y, Kima SY, Ito T, Nakazawab K, Funakia Y, Tadaa T, Hitomia K, Ishii K (2012) J Chromatogr A 1263:28–33

    Article  CAS  Google Scholar 

  16. El-Shahawi MS, Kadi MW, El-Khouly SH, El-Mohty AA, Saad SM, Eweda NEA (2013) J Radioanal Nucl Chem 295:15–22

    Article  CAS  Google Scholar 

  17. Kandwal P, Ansari SA, Mohapatra PK, Manchanda VK (2011) Sep Sci Technol 46:904–911

    Article  CAS  Google Scholar 

  18. Horwitz EP, Dietz ML, Chiarizia R, Diamond H, Maxwell SL, Nelson MR (1995) Anal Chim Acta 310:63–78

    Article  CAS  Google Scholar 

  19. Horwitz EP, Dietz ML, Fisher DE (1991) Anal Chem 63:522–525

    Article  CAS  Google Scholar 

  20. Miro M, Go′mez E, Estela JM, Casas M, Cerda V (2002) Anal Chem 74:826–833

    Article  CAS  Google Scholar 

  21. Sasaki Y, Sugo Y, Suzuki S, Tachimori S (2001) Solvent Extr Ion Exch 19:91–103

    Article  CAS  Google Scholar 

  22. Husain M, Ansari SA, Mohapatra PK, Gupta RK, Parmar VS, Manchanda VK (2008) Desalination 229:294–301

    Article  CAS  Google Scholar 

  23. Ansari SA, Pathak P, Mohapatra PK, Manchanda VK (2012) Chem Rev 112:1751–1772

    Article  CAS  Google Scholar 

  24. Horwitz EP, McAlister DR, Bond AH, Barrans RE (2005) Solvent Ext Ion Exch 23:319–344

    Article  CAS  Google Scholar 

  25. Dutta S, Mohapatra PK, Raut DR, Manchanda VK (2011) J Radioanal Nucl Chem 288:389–394

    Article  CAS  Google Scholar 

  26. Dutta S, Mohapatra PK, Raut DR, Manchanda VK (2011) J of Chromatogr A 1218:6483–6488

    Article  CAS  Google Scholar 

  27. Dutta S, Raut DR, Mohapatra PK (2012) Appl Radiat Isotopes 70:670–675

    Article  CAS  Google Scholar 

  28. Dutta S, Mohapatra PK (2013) J Radioanal Nucl Chem 295:1683–1688

    Article  CAS  Google Scholar 

  29. Michel H, Levent D, Barci V, Barci-Funel G, Hurel C (2008) Talanta 74:1527–1533

    Article  CAS  Google Scholar 

  30. Chiarizia R, Horwitz EP, Dietz ML (1992) Solvent Extr Ion Exch 10–2:337–361

    Article  Google Scholar 

Download references

Acknowledgments

This research was supported by the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology to V.K.M. (R31-2008-10029 under WCU program). Authors would like to acknowledge the cooperation and support of Mr. Sangbok Lee, RI centre, SKKU for experimental work with radionuclides.

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Authors and Affiliations

  1. Department of Energy Science, Sungkyunkwan University, Suwon, 440746, South Korea

    Chirag K. Vyas, Pranav M. Joshirao & Vijay K. Manchanda

  2. School of Electronics and Electrical Engineering, Sungkyunkwan University, Suwon, 440746, South Korea

    Vijay K. Manchanda

Authors
  1. Chirag K. Vyas
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  2. Pranav M. Joshirao
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  3. Vijay K. Manchanda
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Correspondence to Vijay K. Manchanda.

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Vyas, C.K., Joshirao, P.M. & Manchanda, V.K. Separation of 90Y from 90Sr using sequential multiple column extraction chromatography. J Radioanal Nucl Chem 300, 445–450 (2014). https://doi.org/10.1007/s10967-014-2982-8

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