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Determination of elements in kidney, serum and urine of Wistar rats with Acute Renal Insufficiency using NAA

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Abstract

In this investigation ions in serum, urine and kidney of Wistar rats (control group) and Wistar with Acute Renal Insufficiency (ARI) were quantified using instrumental neutron activation analysis. The measurements in serum and urine were performed before, during and after ischemia-induced ARI. The measurements in kidney were performed for the control and ARI groups. Also, a comparative analysis between the concentration ratios before, during and after ARI was performed in urine and serum samples for both groups. The variations results for Cu in serum and I in urine, before and after ischemia-induced ARI, suggest that these elements must be also investigated in renal dysfunction.

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Acknowledgements

The authors thank the financial support of Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).

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Authors and Affiliations

  1. Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN/SP), Av. Lineu Prestes, 2242, 05508-000, São Paulo, SP, Brazil

    Laura C. Oliveira & Cibele B. Zamboni

  2. Departamento de Medicina, Disciplina de Nefrologia, Universidade Federal de São Paulo, Pedro de Toledo, 740, 04023-900, São Paulo, SP, Brazil

    Edson A. Pessoa & Fernanda T. Borges

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  1. Laura C. Oliveira
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  2. Cibele B. Zamboni
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  3. Edson A. Pessoa
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  4. Fernanda T. Borges
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Correspondence to Cibele B. Zamboni.

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Oliveira, L.C., Zamboni, C.B., Pessoa, E.A. et al. Determination of elements in kidney, serum and urine of Wistar rats with Acute Renal Insufficiency using NAA. J Radioanal Nucl Chem 291, 395–398 (2012). https://doi.org/10.1007/s10967-011-1274-9

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  • DOI: https://doi.org/10.1007/s10967-011-1274-9

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