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Challenges and successes in the use of neutron activation analysis procedures for value assignment of animal serum and bovine liver Standard Reference Materials


Analyses for value assignment in the renewal Standard Reference Materials® SRM 1598a Animal Serum and SRM 1577c Bovine Liver included extensive characterization by neutron activation analysis (NAA). Conventional instrumental NAA procedures were complemented by pre-irradiation chemical separations for the determination of Al, V, Mn, and Cu, radiochemical separations for the determination of Ag, As, Cd, Cr, Cu, Mo, Sb, and Se, and the use of (anti-) coincidence gamma-ray spectrometry systems for the instrumental determination of Ag, Cr, and Hg. The previous materials, SRMs 1598, 1577, and 1577b, were analyzed together with the new materials for quality control.

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Certain commercial equipment, instruments, or materials are identified in this paper in order to adequately specify the experimental procedure. Such identification does not imply recommendation or endorsement by the National Institute of Standards and Technology, nor does it imply that the materials or equipment identified are necessarily the best available for the purpose.

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Correspondence to R. Zeisler.

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Zeisler, R., Greenberg, R.R., Mackey, E.A. et al. Challenges and successes in the use of neutron activation analysis procedures for value assignment of animal serum and bovine liver Standard Reference Materials. J Radioanal Nucl Chem 281, 11–15 (2009).

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  • Chemical separation
  • Radiochemistry
  • Gamma-ray spectrometry
  • Low level trace elements