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Influence of the particle size of activated charcoal on labeling efficiency with 67Ga-citrate for colonic transit study

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Abstract

Indium-111 and 99mTc have been proposed for colonic transit study, but 111In is expensive and the half-life of 99mTc is too short for the study. Gallium-67 citrate is inexpensive and has a suitable half-life. In our previous study, we successfully labeled 67Ga-citrate activated charcoal, and the labeling efficiency exceeded 91% after a 96 hour incubation period. In this work, we evaluated the influence of the size of activated charcoal particles on the labeling efficiency with 67Ga-citrate. The data showed that the influence of particle size on the labeling efficiency of activated charcoal with 67Ga was insignificant. Both sizes of activated charcoal particles can be used for labeling with 67Ga in colonic transit study.

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Authors and Affiliations

  1. Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.

    Wan-Yu Lin & Shih-Chuan Tsai

  2. Institute of Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan, R.O.C.

    Kai-Yuan Cheng & Bor-Tsung Hsieh

Authors
  1. Wan-Yu Lin
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  2. Shih-Chuan Tsai
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  3. Kai-Yuan Cheng
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  4. Bor-Tsung Hsieh
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Correspondence to Kai-Yuan Cheng.

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Lin, WY., Tsai, SC., Cheng, KY. et al. Influence of the particle size of activated charcoal on labeling efficiency with 67Ga-citrate for colonic transit study. J Radioanal Nucl Chem 275, 239–242 (2008). https://doi.org/10.1007/s10967-007-6972-y

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  • DOI: https://doi.org/10.1007/s10967-007-6972-y

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