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Nail as a biomarker of selenium and methyl mercury in a rat model

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Abstract

The purpose of this study was to examine the nail response to concurrent intake of methyl mercury (MeHg) and Se. Weanling male Long Evans rats were fed diets containing Se and MeHg. The Se concentration in the nail was well correlated (r 2>0.90) with dietary Se in every MeHg supplementation group. Good correlation was observed between dietary MeHg and nail Hg concentration in every Se group. Exposure to high levels of MeHg resulted in a lower (p<0.03) measured nail Se concentration in the highest Se experimental group relative to control.

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Authors and Affiliations

  1. University of Missouri-Columbia, 601 S College Ave, Columbia, Missouri, 65211, USA

    J. D. Brockman & J. D. Robertson

  2. Research Reactor Center, University of Missouri, Research Park Drive, Columbia, Missouri, 65211, USA

    J. D. Brockman, J. D. Robertson & J. S. Morris

  3. Energy and Environmental Research Center, Grand Forks, ND, 58202-9018, USA

    C. Ralston, L. Raymond & N. Ralston

Authors
  1. J. D. Brockman
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  2. J. D. Robertson
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  3. J. S. Morris
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  4. C. Ralston
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  5. L. Raymond
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  6. N. Ralston
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Correspondence to J. D. Brockman.

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Brockman, J.D., Robertson, J.D., Morris, J.S. et al. Nail as a biomarker of selenium and methyl mercury in a rat model. J Radioanal Nucl Chem 276, 59–64 (2008). https://doi.org/10.1007/s10967-007-0410-z

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  • DOI: https://doi.org/10.1007/s10967-007-0410-z

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