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Synthesis of 14C analogue of 1,2-diaryl-[2-14C]-pyrroles

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Abstract

Three 1,2-diaryl pyrroles selective COX-2 inhibitors, 2-(4-fluorophenyl)-5-methyl-1-(4-methylsulfonyl-phenyl)-1H pyrrole, 2-(4-fluorophenyl)-1-[4-(methylsulfonyl) phenyl]-1H-pyrrole and 4-[2-(4-fluorophenyl)-1H-pyrrol-1-yl]benzenesulfon-amide, all three labeled with 14C in the 2-position were prepared from para-fluoro-benzaldehyde-[carbonyl-14C].

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Authors and Affiliations

  1. Chemical Division, Nuclear Research Center/AEOI, P.O. Box 11365-3486, Tehran, Iran

    N. Saemian, G. Shirvani & H. Matloubi

Authors
  1. N. Saemian
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  2. G. Shirvani
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  3. H. Matloubi
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Correspondence to N. Saemian.

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Saemian, N., Shirvani, G. & Matloubi, H. Synthesis of 14C analogue of 1,2-diaryl-[2-14C]-pyrroles. J Radioanal Nucl Chem 274, 631–634 (2007). https://doi.org/10.1007/s10967-006-6943-8

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  • DOI: https://doi.org/10.1007/s10967-006-6943-8

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