Skip to main content
SpringerLink
Log in

Synthesis of a 14C analogue of N-(3,5-dichlorobenzyl)-4-(fluoromethoxy) benzene carboximidamide-[carboxy-14C] as NR2B-selective NMDA receptor antagonist

  • Short Cummunication
  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

N-(3,5-Dichlorobenzyl)-4-(fluoromethoxy) benzenecarboximidamide labeled with carbon-14 was prepared from 4-hydroxy-benzonitrile-[cyano-14C].

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. H. Mori, M. Mishina, Neuropharm, 34 (1995) 1219.

    Article  CAS  Google Scholar 

  2. R. Betarbet, R. Porter, J. T. Greenamyre, J. Neurochem., 74 (2000) 1166.

    Article  CAS  Google Scholar 

  3. A. Buller, H. Larson, B. Schneider, J. Beaton, R. Morrisett, D. Monaghan, J. Neurosci., 14 (1994) 5471.

    CAS  Google Scholar 

  4. R. Dingledine, K. Borges, D. Bowie, S. Traynelis, Pharmacol. Rev., 51 (1999) 7.

    CAS  Google Scholar 

  5. H. Monyer, N. Burnashev, D. J. Laurie, B. Sakmann, P. H. Seeburg, Neuron, 12 (1994) 529.

    Article  CAS  Google Scholar 

  6. B. A. Chizh, P. M. Headley, T. M. Tzchentke, Trends Pharmacol. Sci., 22 (2001) 636.

    Article  CAS  Google Scholar 

  7. S. Boyce, A. Wyatt, J. K. Webb, R. O’Donnell, G. Mason, M. Rigby, D. Sirinathsinghji, R. G. Hill, N. M. Rupniak, Neuropharm., 38 (1999) 611.

    Article  CAS  Google Scholar 

  8. J. Johnson, P. Ascher, Nature, 325 (1987) 529.

    Article  CAS  Google Scholar 

  9. T. Haradahira, J. Maeda, T. Okauchi, M. R. Zhang, J. Hojo, T. Kida, T. Arai, F. Yamamato, S. Sasaki, M. Maeda, K. Suzuki, T. Suhara, Nucl. Med. Biol., 29 (2002) 517.

    Article  CAS  Google Scholar 

  10. C. F. Clairborne, J. A. McCauley, B. E. Libby, N. R. Curtis, H. J. Diggle, J. J. Kulagowski, S. R. Michelson, K. D. Anderson, D. A. Claremon, R. M. Freidinger, R. A. Bednar, S. D. Mosser, S. L. Gaul, T. M. Connolly, C. L. Condra, B. Bednar, G. L. Stump, J. J. Lynch, A. Macaulay, K. A. Wafford, K. S. Koblan, N. J. Liverton, Bioorg. Med. Chem. Lett., 13 (2003) 697.

    Article  Google Scholar 

  11. T. G. Hamill, J. A. McCauley, H. D. Burns, J. Labelled Comp. Radiopharm., 48 (2005) 1.

    Article  CAS  Google Scholar 

  12. N. Saemian, G. Shirvani, H. Matloubi, J. Labelled Comp. Radiopharm., 49 (2006) 71.

    Article  CAS  Google Scholar 

  13. C. W. Perry, W. Burger, C. M. Dlaney, J. Labelled Comp. Radiopharm., 16 (1978) 645.

    Article  Google Scholar 

  14. N. Saemian, G. Shirvani, H. Matloubi, Nukleonika, 50 (2005) 139.

    CAS  Google Scholar 

  15. D. Seidel, P. Brehmer, Y. Schoof, U. Weinber, U. Niewohner, M. Nowakowski, J. Labelled Comp. Radiopharm., 46 (2003) 1019.

    Article  CAS  Google Scholar 

  16. N. Saemian, G. Shirvani, H. Matloubi, J. Radioanal. Nucl. Chem., 268 (2006) 545.

    Article  CAS  Google Scholar 

  17. J. Sandel, O. Langer, P. Larsen, F. Dolle, F. Vaufrey, S. Demphel, C. Crouzel, C. Hanlldin, J. Labelled Comp. Radiopharm., 43 (2000) 331.

    Article  Google Scholar 

  18. N. R. Curtis, H. J. Diggle, J. J. Kulagowski, C. Londen, S. Grimwood, P. H. Hutson, F. Murray, P. Richards, A. Macaulay, K. A. Wafford, Bioorg. Med. Chem. Lett., 13 (2003) 693.

    Article  CAS  Google Scholar 

  19. C. Thominiaux, B. Bruin, Y. Bramoulle, F. Hinnen, S. Demphel, H. Valette, M. Bottlaender, L. Besret, M. Kassiou, F. Dolle, Appl. Radiation Isotopes, 64 (2006) 343.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chemical Division, Nuclear Research Center/AEOI, P.O. Box 11365-3486, Tehran, Iran

    N. Saemian, G. Shirvani & H. Matloubi

Authors
  1. N. Saemian
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Shirvani
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Matloubi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to N. Saemian.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Saemian, N., Shirvani, G. & Matloubi, H. Synthesis of a 14C analogue of N-(3,5-dichlorobenzyl)-4-(fluoromethoxy) benzene carboximidamide-[carboxy-14C] as NR2B-selective NMDA receptor antagonist. J Radioanal Nucl Chem 274, 643–645 (2007). https://doi.org/10.1007/s10967-006-6940-y

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10967-006-6940-y

Keywords

Search

Navigation