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Synthesis of N-alkyl- and N-alkenyl-substituted polyanilines. Properties and antibacterial activity study

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Abstract

Polyaniline derivatives were synthesized, characterized and evaluated for their antibacterial activities. By chemical oxidative polymerization, N-substituted polyaniline derivatives containing alkyl and alkenyl fragments in the main chain were obtained. NMR, UV-Vis, FT-IR were used to characterize the chemical structures of the polymers. SEM images revealed the different shapes and surface morphology of the polymers. In addition, the multi-step thermal degradation behavior of the polymers and the higher stability of the N-alkenyl PANIs compared to the N-alkyl PANIs were observed from the TGA plots. These polymers were used as antimicrobial agents against both gram-positive (Bacillus subtilis) and gram-negative (Pseudomonas aureofaciens) bacteria. For both gram-positive and gram-negative test strains, the highest antibacterial activity was observed for N-allyl-PANI and N-cyclohexenyl-PANI. The diameter of the inhibition zone was obtained within the range for Bacillus subtilis up to 23 mm and 24 mm, and for Pseudomonas aureofaciens up to 36 mm and 28 mm, respectively. Therefore, these polymers could be potential candidates for biomedical applications.

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All of the data sets that were included and/or examined in the present study can be obtained from the corresponding author upon request.

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Acknowledgment

This work was supported by the Ministry of Science and Higher Education of the Russian Federation as part of the state task no. 122031400278-2.

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Authors and Affiliations

  1. Laboratory of organic functional materials, Ufa Institute of Chemistry of the Russian Academy of Sciences, Ufa, Russia

    Lyaysan R. Latypova, Gulsum S. Usmanova, Anastasia N. Andriianova, Samil M. Salikhov & Akhat G. Mustafin

  2. Ufa State Petroleum Technological University, Ufa, 450064, Russia

    Liliya Ya. Vasilova & Vladimir V. Zorin

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  1. Lyaysan R. Latypova
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  2. Gulsum S. Usmanova
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  3. Liliya Ya. Vasilova
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  4. Anastasia N. Andriianova
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  5. Samil M. Salikhov
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  6. Vladimir V. Zorin
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  7. Akhat G. Mustafin
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Correspondence to Lyaysan R. Latypova.

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Latypova, L.R., Usmanova, G.S., Vasilova, L.Y. et al. Synthesis of N-alkyl- and N-alkenyl-substituted polyanilines. Properties and antibacterial activity study. J Polym Res 30, 315 (2023). https://doi.org/10.1007/s10965-023-03696-5

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